YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: PARP2_ARATH

General Information:
Name(s) found: PARP2_ARATH [Swiss-Prot]
Description(s) found:
Found 12 descriptions.
SHOW ALL
  • Poly [ADP-ribose] polymerase 2 OS=Arabidopsis thaliana GN=PARP2 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 637 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    Biological Process: protein amino acid ADP-ribosylation [IEA][ISS]
    Molecular Function: nucleic acid binding [IEA]
    NAD+ ADP-ribosyltransferase activity [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANKLKVDEL RLKLAERGLS TTGVKAVLVE RLEEAIAEDT KKEESKSKRK RNSSNDTYES  60
   61 NKLIAIGEFR GMIVKELREE AIKRGLDTTG TKKDLLERLC NDANNVSNAP VKSSNGTDEA 120
  121 EDDNNGFEEE KKEEKIVTAT KKGAAVLDQW IPDEIKSQYH VLQRGDDVYD AILNQTNVRD 180
  181 NNNKFFVLQV LESDSKKTYM VYTRWGRVGV KGQSKLDGPY DSWDRAIEIF TNKFNDKTKN 240
  241 YWSDRKEFIP HPKSYTWLEM DYGKEENDSP VNNDIPSSSS EVKPEQSKLD TRVAKFISLI 300
  301 CNVSMMAQHM MEIGYNANKL PLGKISKSTI SKGYEVLKRI SEVIDRYDRT RLEELSGEFY 360
  361 TVIPHDFGFK KMSQFVIDTP QKLKQKIEMV EALGEIELAT KLLSVDPGLQ DDPLYYHYQQ 420
  421 LNCGLTPVGN DSEEFSMVAN YMENTHAKTH SGYTVEIAQL FRASRAVEAD RFQQFSSSKN 480
  481 RMLLWHGSRL TNWAGILSQG LRIAPPEAPV TGYMFGKGVY FADMFSKSAN YCYANTGAND 540
  541 GVLLLCEVAL GDMNELLYSD YNADNLPPGK LSTKGVGKTA PNPSEAQTLE DGVVVPLGKP 600
  601 VERSCSKGML LYNEYIVYNV EQIKMRYVIQ VKFNYKH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..105] PSI-BLAST 7.154902 Solution structure of BRCT domain of poly(ADP-ribose) polymerase-1
    2 View Details [106..272] PSI-BLAST 36.69897 Solution structure of WGR domain of poly(ADP-ribose) polymerase-1
    3 View Details [273..637] PSI-BLAST 124.0 Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase with a novel inhibitor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • NAD+ ADP-ribosyltransferase activity
    		•  7.15093533922724 bayes_pls_golite062009
  • NAD(P)+-protein-arginine ADP-ribosyltransferase activity
    		•  2.57756389034544 bayes_pls_golite062009
  • binding
    		•  1.5526011325617 bayes_pls_golite062009
  • transferase activity
    		•  1.5222353301058 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.901890891144085 bayes_pls_golite062009
  • catalytic activity
    		•  0.886617552734979 bayes_pls_golite062009
  • DNA binding
    		•  0.850361767185031 bayes_pls_golite062009
  • protein binding
    		•  0.610837485187136 bayes_pls_golite062009
  • NAD+ nucleosidase activity
    		•  0.309947239058532 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  0.29605207876765 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.209002662548996 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.147630885386744 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  0.0346323577656257 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle