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Protein Overview: DNMT1_ARATH

General Information:
Name(s) found: DNMT1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|462650|sp|P34881.1|DNMT1_ARATH RecName: Full=DNA (cytosine-5)-methyltransferase AthI; Short=DNA methyltransferase AthI; Short=DNA Metase AthI; Short=M.AthI [NCBI NR]
  • gi|304107|gb|AAA32829.1| cytosine-5 methyltransferase [NCBI NR]
  • gi|15239810|ref|NP_199727.1| MET1 (METHYLTRANSFERASE 1); methyltransferase [Arabidopsis thaliana] [NCBI NR]
  • gi|1363480|pir||S59604 DNA (cytosine-5-)-methyltransferase (EC 2.1.1.37) - Arabidopsis thaliana [NCBI NR]
  • gi|10177145|dbj|BAB10334.1| DNA (cytosine-5)-methyltransferase [Arabidopsis thaliana] [NCBI NR]
  • DNA (cytosine-5)-methyltransferase 1 OS=Arabidopsis thaliana GN=DMT1 PE=1 SV=1 [Swiss-Prot]
  • (P34881) DNA (cytosine-5)-methyltransferase AthI (EC 2.1.1.37) (DNA methyltransferase AthI) (DNA Metase AthI) (M.AthI) [Swiss-Prot]
  • DNA (cytosine-5)-methyltransferase [Arabidopsis thaliana]gi|462650|sp|P34881|DNM1_ARATH DNA (cytosine-5)-methyltransferase AthI (DNA methyltransferase AthI) (DNA Metase AthI) (M.AthI)gi|1363480|pir||S59604 DNA (cytosine-5-)-methyltransferase (EC 2.1.1.3 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 DNA [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: METI, DDM2, DMT01, MET2, DMT1, MET1 | MET1 (DECREASED METHYLATION 2DNA) | chr5:19949727-19955412 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • DNA (cytosine-5)-methyltransferase AthI (DNA methyltransferase AthI) (DNA Metase AthI) (M.AthI) [nr-271106-contam.fasta]
  • MET1 (DECREASED METHYLATION 2DNA) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • DNA (cytosine-5)-methyltransferase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • cytosine-5 methyltransferase [nr-271106-contam.fasta]
  • | Symbols: MET1, MET2, METI, DDM2, DMT01, DMT1 | methyltransferase 1 | chr5:19932501-19938186 FORWARD LENGTH=1534 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 1534 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: DNA mediated transformation [IMP]
    regulation of gene expression by genetic imprinting [IMP]
    DNA methylation on cytosine within a CG sequence [IMP]
    maintenance of DNA methylation [IMP]
    negative regulation of flower development [IMP]
    zygote asymmetric cytokinesis in the embryo sac [IMP]
    Molecular Function: methyltransferase activity [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVENGAKAAK RKKRPLPEIQ EVEDVPRTRR PRRAAACTSF KEKSIRVCEK SATIEVKKQQ  60
   61 IVEEEFLALR LTALETDVED RPTRRLNDFV LFDSDGVPQP LEMLEIHDIF VSGAILPSDV 120
  121 CTDKEKEKGV RCTSFGRVEH WSISGYEDGS PVIWISTELA DYDCRKPAAS YRKVYDYFYE 180
  181 KARASVAVYK KLSKSSGGDP DIGLEELLAA VVRSMSSGSK YFSSGAAIID FVISQGDFIY 240
  241 NQLAGLDETA KKHESSYVEI PVLVALREKS SKIDKPLQRE RNPSNGVRIK EVSQVAESEA 300
  301 LTSDQLVDGT DDDRRYAILL QDEENRKSMQ QPRKNSSSGS ASNMFYIKIN EDEIANDYPL 360
  361 PSYYKTSEEE TDELILYDAS YEVQSEHLPH RMLHNWALYN SDLRFISLEL LPMKQCDDID 420
  421 VNIFGSGVVT DDNGSWISLN DPDSGSQSHD PDGMCIFLSQ IKEWMIEFGS DDIISISIRT 480
  481 DVAWYRLGKP SKLYAPWWKP VLKTARVGIS ILTFLRVESR VARLSFADVT KRLSGLQAND 540
  541 KAYISSDPLA VERYLVVHGQ IILQLFAVYP DDNVKRCPFV VGLASKLEDR HHTKWIIKKK 600
  601 KISLKELNLN PRAGMAPVAS KRKAMQATTT RLVNRIWGEF YSNYSPEDPL QATAAENGED 660
  661 EVEEEGGNGE EEVEEEGENG LTEDTVPEPV EVQKPHTPKK IRGSSGKREI KWDGESLGKT 720
  721 SAGEPLYQQA LVGGEMVAVG GAVTLEVDDP DEMPAIYFVE YMFESTDHCK MLHGRFLQRG 780
  781 SMTVLGNAAN ERELFLTNEC MTTQLKDIKG VASFEIRSRP WGHQYRKKNI TADKLDWARA 840
  841 LERKVKDLPT EYYCKSLYSP ERGGFFSLPL SDIGRSSGFC TSCKIREDEE KRSTIKLNVS 900
  901 KTGFFINGIE YSVEDFVYVN PDSIGGLKEG SKTSFKSGRN IGLRAYVVCQ LLEIVPKESR 960
  961 KADLGSFDVK VRRFYRPEDV SAEKAYASDI QELYFSQDTV VLPPGALEGK CEVRKKSDMP1020
 1021 LSREYPISDH IFFCDLFFDT SKGSLKQLPA NMKPKFSTIK DDTLLRKKKG KGVESEIESE1080
 1081 IVKPVEPPKE IRLATLDIFA GCGGLSHGLK KAGVSDAKWA IEYEEPAGQA FKQNHPESTV1140
 1141 FVDNCNVILR AIMEKGGDQD DCVSTTEANE LAAKLTEEQK STLPLPGQVD FINGGPPCQG1200
 1201 FSGMNRFNQS SWSKVQCEMI LAFLSFADYF RPRYFLLENV RTFVSFNKGQ TFQLTLASLL1260
 1261 EMGYQVRFGI LEAGAYGVSQ SRKRAFIWAA APEEVLPEWP EPMHVFGVPK LKISLSQGLH1320
 1321 YAAVRSTALG APFRPITVRD TIGDLPSVEN GDSRTNKEYK EVAVSWFQKE IRGNTIALTD1380
 1381 HICKAMNELN LIRCKLIPTR PGADWHDLPK RKVTLSDGRV EEMIPFCLPN TAERHNGWKG1440
 1441 LYGRLDWQGN FPTSVTDPQP MGKVGMCFHP EQHRILTVRE CARSQGFPDS YEFAGNINHK1500
 1501 HRQIGNAVPP PLAFALGRKL KEALHLKKSP QHQP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..251] MSA 1.084977 View MSA. No confident structure predictions are available.
    2 View Details [252..580] PSI-BLAST 15.69897 No description for 2r10A was found.
    3 View Details [581..688] deduced N/A No confident structure predictions are available.
    4 View Details [689..923] PSI-BLAST 30.69897 Crystal structure of the proximal BAH domain of polybromo
    5 View Details [924..1075] MSA 1.153991 View MSA. No confident structure predictions are available.
    6 View Details [1076..1534] PSI-BLAST 55.221849 DNA methylase HaeIII


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle