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Protein Overview: HMA5_ARATH

General Information:
Name(s) found: HMA5_ARATH [Swiss-Prot]
Description(s) found:
Found 29 descriptions.
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  • Probable copper-transporting ATPase HMA5 OS=Arabidopsis thaliana GN=HMA5 PE=1 SV=2 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 995 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    integral to membrane [IEA]
    Biological Process: detoxification of copper ion [IMP]
    response to copper ion [IMP]
    Molecular Function: ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATKLLSLTC IRKERFSERY PLVRKHLTRS RDGGGGSSSE TAAFEIDDPI SRAVFQVLGM  60
   61 TCSACAGSVE KAIKRLPGIH DAVIDALNNR AQILFYPNSV DVETIRETIE DAGFEASLIE 120
  121 NEANERSRQV CRIRINGMTC TSCSSTIERV LQSVNGVQRA HVALAIEEAE IHYDPRLSSY 180
  181 DRLLEEIENA GFEAVLISTG EDVSKIDLKI DGELTDESMK VIERSLEALP GVQSVEISHG 240
  241 TDKISVLYKP DVTGPRNFIQ VIESTVFGHS GHIKATIFSE GGVGRESQKQ GEIKQYYKSF 300
  301 LWSLVFTVPV FLTAMVFMYI PGIKDLLMFK VINMLTVGEI IRCVLATPVQ FVIGWRFYTG 360
  361 SYKALRRGSA NMDVLIALGT NAAYFYSLYT VLRAATSPDF KGVDFFETSA MLISFIILGK 420
  421 YLEVMAKGKT SQAIAKLMNL APDTAILLSL DKEGNVTGEE EIDGRLIQKN DVIKIVPGAK 480
  481 VASDGYVIWG QSHVNESMIT GEARPVAKRK GDTVIGGTLN ENGVLHVKVT RVGSESALAQ 540
  541 IVRLVESAQL AKAPVQKLAD RISKFFVPLV IFLSFSTWLA WFLAGKLHWY PESWIPSSMD 600
  601 SFELALQFGI SVMVIACPCA LGLATPTAVM VGTGVGASQG VLIKGGQALE RAHKVNCIVF 660
  661 DKTGTLTMGK PVVVKTKLLK NMVLREFYEL VAATEVNSEH PLAKAIVEYA KKFRDDEENP 720
  721 AWPEACDFVS ITGKGVKATV KGREIMVGNK NLMNDHKVII PDDAEELLAD SEDMAQTGIL 780
  781 VSINSELIGV LSVSDPLKPS AREAISILKS MNIKSIMVTG DNWGTANSIA REVGIDSVIA 840
  841 EAKPEQKAEK VKELQAAGHV VAMVGDGIND SPALVAADVG MAIGAGTDIA IEAADIVLMK 900
  901 SNLEDVITAI DLSRKTFSRI RLNYVWALGY NLMGIPIAAG VLFPGTRFRL PPWIAGAAMA 960
  961 ASSVSVVCCS LLLKNYKRPK KLDHLEIREI QVERV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..115] PSI-BLAST 26.0 No description for 2rmlA was found.
    2 View Details [116..201] Pfam 8.853872 No description for PF00403.18 was found. No confident structure predictions are available.
    3 View Details [202..269] PSI-BLAST 11.0 Solution structure of the apo form of the sixth soluble domain A69P mutant of Menkes protein
    4 View Details [270..370] deduced N/A No confident structure predictions are available.
    5 View Details [371..680] PSI-BLAST 57.69897 Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M
    6 View Details [681..995] PSI-BLAST 59.69897 CopA ATP Binding Domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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