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Protein Overview: cye-1

General Information:
Name(s) found: cye-1 / CE33761 [WormBase]
Description(s) found:
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  • WBGene00000871 locus:cye-1 G1\/S-specific cyclin-E status:Confirmed UniProt:O01501 protein_id:CCD66922.1 [WormBase]
  • gi|71981558|ref|NP_001021028.1| CYclin E family member (cye-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|30025129|gb|AAP13781.1| Cyclin e protein 1, isoform b [Caenorhabditis elegans] [NCBI NR]
  • [wormpep104.fasta]
  • Cyclin e protein 1, isoform b [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE33761 WBGene00000871 locus:cye-1 status:Confirmed SW:O01501 protein_id:AAP13781.1 [wormpep150.fasta]
  • 33761 WBGene00000871 locus:cye-1 status:Partially_confirmed SW:O01501 protein_id:AAP13781.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • CE33761 WBGene00000871 locus:cye-1 status:Partially_confirmed SW:O01501 protein_id:AAP13781.1 [wormpep132.fasta]
  • 33761 WBGene00000871 locus:cye-1 status:Confirmed SW:O01501 protein_id:AAP13781.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • locus:cye-1 status:Predicted SW:O01501 protein_id:AAP13781.1 [wormpep115.fasta.reversed]
  • CE33761 WBGene00000871 locus:cye-1 status:Confirmed UniProt:O01501 protein_id:AAP13781.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE33761 WBGene00000871 locus:cye-1 status:Confirmed UniProt:O01501 protein_id:AAP13781.1| [wormORF-contam.fasta]
  • C37A2.4b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE33761 WBGene00000871 locus:cye-1 status:Confirmed UniProt:O01501 protein_id:CCD66922.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE33761 WBGene00000871 locus:cye-1 status:Confirmed UniProt:O01501 protein_id:CCD66922.1 G1\/S-specific cyclin-E [wormpep246-ecoli-contam.fasta]
  • Isoform of O01501, Isoform b of G1/S-specific cyclin-E OS=Caenorhabditis elegans GN=cye-1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 521 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cyclin-dependent protein kinase holoenzyme complex [ISSLink to PubMed article]
    Biological Process: germ cell development [IMPLink to PubMed article]
    embryonic cleavage [IMPLink to PubMed article]
    positive regulation of vulval development [IMPLink to PubMed article]
    positive regulation of cyclin-dependent protein kinase activity [ISSLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    post-embryonic development [IMPLink to PubMed article]
    positive regulation of cell proliferation [IMPLink to PubMed article]
    DNA endoreduplication [IMPLink to PubMed article]
    cytokinesis [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    G1/S transition of mitotic cell cycle [IMPLink to PubMed article]
    Molecular Function: cyclin-dependent protein kinase regulator activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGRKSSRTA ERVPTTQKPE RKSAILSPHD ELRERLLETA IDMKENIPQR NTRNSSVGSQ  60
   61 KSDCSETRKR RSTKEGPAAK RHSGEKHRNG SREDSLEYIS DDREVGSSSS QSSRTRGQPL 120
  121 PAMPEEEEVF DKSSSSDNLA ESEESHEMVR LEERQDIEEE IEDDFDDEEE DVVNDKEEYE 180
  181 EIESEDEDDY PVQNEGFAVT KRLMNDEHMV TAPTFLSTAK CDGIGSPTKV WSLMVKRDEI 240
  241 PRATRFLLGN HPDMDDEKRR ILIDWMMEVC ESEKLHRETF HLAVDYVDRY LESSNVECST 300
  301 DNFQLVGTAA LFIAAKYEEI YPPKCIDFAH LTDSAFTCDN IRTMEVLIVK YIGWSLGPIT 360
  361 SIQWLSTYLQ LLGTGKKNKS DHYEEQNMYV PELLRSEYLE MCKILDFLLF EIDSFTFSYR 420
  421 TIAAAVLFVN YEPTCAVEKA TGFMQAQLEK VIEYVEPVCR AFAKQRQLLD DVIPKHESIK 480
  481 SDDSHNIQVY VKRSSMEPIV KSERERIQHL KARRLHPQRL F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..217] MSA 13.314996 View MSA. No confident structure predictions are available.
    2 View Details [218..521] PSI-BLAST 50.045757 The structural basis of CDK2 activation by cyclin E


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle