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Protein Overview: bpl-1

General Information:
Name(s) found: bpl-1 / CE32623 [WormBase]
Description(s) found:
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  • WBGene00000259 locus:bpl-1 status:Confirmed UniProt:G5ECZ9 protein_id:CCD66051.1 [WormBase]
  • gi|46452276|gb|AAS98221.1| biotin protein ligase, holocarboxylase synthetase (70.9 kD) alternative variant b [Caenorhabditis elegans] [NCBI NR]
  • gi|32563942|ref|NP_871920.1| Biotin Protein Ligase family member (bpl-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|24943025|gb|AAN65327.1| Hypothetical protein F13H8.10b [Caenorhabditis elegans] [NCBI NR]
  • [wormpep104.fasta]
  • CE32623 WBGene00000259 locus:bpl-1 status:Confirmed TR:Q8IG27 protein_id:AAN65327.1 [wormpep150.fasta]
  • 32623 WBGene00000259 locus:bpl-1 status:Confirmed TR:Q8IG27 protein_id:AAN65327.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • biotin/lipoate A/B protein ligase domain containing protein family member (70.9 kD) (2G569) [Caenorhabditis elegans]gi|24943025|gb|AAN65327.1| Biotin protein ligase protein 1, isoform b [Caenorhabditis elegans]gi|46452276|gb|AAS98221.1| biotin protein l [nrdb_11152004_Chlamydomonas]
  • status:Partially_confirmed TR:Q8IG27 protein_id:AAN65327.1 [wormpep115.fasta.reversed]
  • CE32623 WBGene00000259 locus:bpl-1 status:Confirmed UniProt:Q8IG27_CAEEL protein_id:AAN65327.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE32623 WBGene00000259 locus:bpl-1 status:Confirmed UniProt:Q8IG27_CAEEL protein_id:AAN65327.1| [wormORF-contam.fasta]
  • Biotin Protein Ligase family member (bpl-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • biotin protein ligase, holocarboxylase synthetase (70.9 kD) alternative variant b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Biotin protein ligase protein 1, isoform b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE32623 WBGene00000259 locus:bpl-1 status:Confirmed UniProt:Q8IG27 protein_id:AAN65327.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE32623 WBGene00000259 locus:bpl-1 status:Confirmed UniProt:G5ECZ9 protein_id:CCD66051.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Isoform of Q9BI98, Biotin Protein Ligase OS=Caenorhabditis elegans GN=bpl-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 632 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: protein modification process [IEALink to PubMed article]
    Molecular Function: catalytic activity [IEALink to PubMed article]
    biotin-[acetyl-CoA-carboxylase] ligase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFPRVISNA RHIALLFTGD RGRSVSPSFE YYQNRSLRGF TSAANPHRVA TRNSTVRQVP  60
   61 LYQFLTSRSS SFKAMCKPNS VLVYTGGNDS LYSDIRHRLS FLLPPDEITV FNVSIQALKK 120
  121 QPWAEKSTVC VILASTNDLD DEAWEKIQAY FNQNGKIIFV CQNKLLASIT GCDSSKANAS 180
  181 ILRFAFGSQN NKLKDTNKEF VKFLEKNMKK LPKSTAINET FRSKDVSVGA NFTVVLKKEP 240
  241 DAPLFLYMQN NGSLHASALF SDATTQQLIA PNSNLLKDSL RSVGVNVCDT TMPPLTKGIL 300
  301 IAEYDSIIES IAGLRLGEEI GLQPRILLRK SDVVEELGLP EATEKLLPIE VVNRDSDAGT 360
  361 SKNFDFNLYF EQIHSKIGQV VLLVDVATTT MDIIESVNAG IPSLESVVVI ANRQISGRGR 420
  421 GGNEFLCPRG MAMFNFSFSI SKKSRIAKHL PILQHIFCVA LVEAARNLSG YPEFPLHIKW 480
  481 PNDLYCERSH KVGGMLLQCS TRDDSFRVSI GCGMNVSNDK PTMCLNDMLP KEAETRITKE 540
  541 QLIAETINKF TYYMKDYEDN GPETFKKKYH EYWLHSQQEV LLSDFNERVT IRGIDDDGYL 600
  601 QVRSKSNPDK IFSIGDDGNT FDMMKGLIRH KY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..289] FFAS03 1.4 Three-dimensional Structure of YaaE from Bacillus subtilis
    2 View Details [290..632] PSI-BLAST 79.30103 THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA-BINDING DOMAINS

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.314728592960672 bayes_pls_golite062009
    2
    Term Confidence Notes
  • ligase activity
    		•  1.67554521587144 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  1.61832657533856 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  1.61646092552736 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  1.61646092552736 bayes_pls_golite062009
  • catalytic activity
    		•  1.09322413032596 bayes_pls_golite062009
  • transcription factor activity
    		•  0.209693003149741 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle