Protein Overview: CE32237

General Information:
Name(s) found:	CE32237 [WormBase]
Description(s) found: Found 18 descriptions. SHOW ALL	WBGene00021227 locus:mct-1 status:Predicted UniProt:Q9UAT3 protein_id:CCD64369.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	544 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [IEA]
Biological Process:	transport [IEA] organic anion transport [IEA]
Molecular Function:	secondary active monocarboxylate transmembrane transporter activity [IEA] transporter activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKQPIDGPL DAEKKEVTVA VTAAENFEEQ VEEVGKVTPP DGGYGWVVVA ASFLVNMAVD  60
   61 GVIYTCGKIL VPIWADQFGS TSVAGAVISI LTGCYYLAGP LASSFVNVFG IRSVAIAGSI 120
  121 LATTAFLLSR FASTIWELYL LFGVLGGIGF GCMYLPSIVI LSTYFAKKRS VATGIAVCGS 180
  181 GIGTMVFSTI NGPVFDYFGK DVGSFMVYLA AIAISGSLFS LLFAPLKATE HQVKKVAKMV 240
  241 RNYEGKPEEP TQRLLEDVRN DLEELNRPGH NADTFYAGNA PVSRSRSNTL DRKAAESAEA 300
  301 HVVHATEHHT VHHVVKKSKF TKFKESLCSV LDKDLLFSPS FMTLAVSGTF TVLSFLVPFV 360
  361 YLALAMKQKN PDFTDAELSL PVTLIGAFNI MFRIGCGMVA DHPKMSALQV SNVATIIAGT 420
  421 SMLFVPFCTE LWHYVVFCIP FSAGVACFAA LRSVICVELI GVEKLSNAFG ILMVFMGIGA 480
  481 VVGGPIAAQI KDITGNYDIS FYVMGIIFAF SGVMTIRLPE LKAWEESKKL ARAGTEMRVI 540
  541 SEAS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..444]	PSI-BLAST	16.30103	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
2	View Details	[445..544]	FFAS03	1.9	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
transporter activity	4.09176719149278	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.54194478414824	bayes_pls_golite062009
ion transmembrane transporter activity	2.21266150105753	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.15783210522667	bayes_pls_golite062009
cation transmembrane transporter activity	1.79369588808394	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
binding	0.805286077372817	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009

2

Term	Confidence	Notes
transporter activity	3.82096685159505	bayes_pls_golite062009
transmembrane transporter activity	3.34396155292818	bayes_pls_golite062009
substrate-specific transporter activity	3.32643461660963	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.2506965512085	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.05049771748124	bayes_pls_golite062009
ion transmembrane transporter activity	2.02370427376594	bayes_pls_golite062009
cation transmembrane transporter activity	1.62538016506437	bayes_pls_golite062009
active transmembrane transporter activity	1.46819549608723	bayes_pls_golite062009
secondary active transmembrane transporter activity	0.869150152038001	bayes_pls_golite062009
binding	0.816478136738584	bayes_pls_golite062009
polyol transmembrane transporter activity	0.339747214378126	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.339747214378126	bayes_pls_golite062009
symporter activity	0.327558013224678	bayes_pls_golite062009
solute:cation symporter activity	0.327558013224678	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.222664452597504	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

Philius confidence legend

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