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Protein Overview: nhx-3

General Information:
Name(s) found: nhx-3 / CE32044 [WormBase]
Description(s) found:
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  • WBGene00003731 locus:nhx-3 Probable Na(+)\/H(+) antiporter nhx-3 status:Confirmed UniProt:O16452 protein_id:CCD62992.1 [WormBase]
  • gi|71987535|ref|NP_001023735.1| Na/H eXchanger family member (nhx-3) [Caenorhabditis elegans] [NCBI NR]
  • gi|29429156|sp|O16452.2|NHX3_CAEEL RecName: Full=Probable Na(+)/H(+) antiporter nhx-3; AltName: Full=Na(+)-H(+) exchanger protein 3 [NCBI NR]
  • ref|NP_504943.2| Na/H eXchanger, associated to intracellular granules or organelles in the main epidermal cell syncytium hyp7, in adult distal uterine cells and pore /socket cells (75.5 kD) (nhx-3) [Caenorhabditis elegans] [NCBI NR]
  • gi|24418279|gb|AAG24015.2| Na/h exchanger protein 3, isoform a [Caenorhabditis elegans] [NCBI NR]
  • gi|20269918|gb|AAM18103.1|AF497825_1 putative Na-H exchanger isoform 3 [Caenorhabditis elegans] [NCBI NR]
  • Probable Na(+)/H(+) antiporter nhx-3 OS=Caenorhabditis elegans GN=nhx-3 PE=2 SV=2 [Swiss-Prot]
  • (O16452) Probable Na(+)/H(+) antiporter nhx-3 (Na(+)-H(+) exchanger protein 3) [Swiss-Prot]
  • [wormpep104.fasta]
  • CE32044 WBGene00003731 locus:nhx-3 status:Confirmed SW:O16452 protein_id:AAG24015.2 [wormpep150.fasta]
  • 32044 WBGene00003731 locus:nhx-3 status:Confirmed SW:O16452 protein_id:AAG24015.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • Na/H eXchanger, associated to intracellular granules or organelles in the main epidermal cell syncytium hyp7, in adult distal uterine cells and pore /socket cells (75.5 kD) (nhx-3) [Caenorhabditis elegans]gi|24418279|gb|AAG24015.2| Na/h exchanger protein [nrdb_11152004_Chlamydomonas]
  • locus:nhx-3 status:Confirmed SW:O16452 protein_id:AAG24015.2 [wormpep115.fasta.reversed]
  • CE32044 WBGene00003731 locus:nhx-3 status:Confirmed UniProt:O16452 protein_id:AAG24015.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE32044 WBGene00003731 locus:nhx-3 status:Confirmed UniProt:O16452 protein_id:AAG24015.2| [wormORF-contam.fasta]
  • putative Na-H exchanger isoform 3 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Probable Na(+)/H(+) antiporter nhx-3 (Na(+)-H(+) exchanger protein 3) [nr-271106-contam.fasta]
  • Na/h exchanger protein 3, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Na/H eXchanger family member (nhx-3) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE32044 WBGene00003731 locus:nhx-3 status:Confirmed UniProt:O16452 protein_id:CCD62992.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE32044 WBGene00003731 locus:nhx-3 status:Confirmed UniProt:O16452 protein_id:CCD62992.1 Probable Na(+)\/H(+) antiporter nhx-3 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 670 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: sodium ion transport [IEALink to PubMed article]
    regulation of pH [IEALink to PubMed article]
    Molecular Function: solute:hydrogen antiporter activity [IEALink to PubMed article]
    sodium:hydrogen antiporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSKLFVFLL ICYATADEVD KKEAKHGFQL FHWNWDHIHK VYVITTWLLV ASLAKILFNL  60
   61 MKPLSKWLPD SSLLIIVGLG LGYFLNQTTL SGVHLDSHAF FLYLLPPIIF DAGYFMPNRA 120
  121 LFKNFDSVLV FSVLGTLWNT FAIGGSLLIM SKYQLFTMPF TTFEILVFSA LISAVDPVAV 180
  181 IAIFEEIHVN EFLFINVFGE ALFNDGVTVV LYQMFKSFAL IGSENLSPWD YATGGLSFFV 240
  241 VALGGAAIGI IFAIATSLAT KYTQGIKILA PVFIFLLPYM AYLTAEMVSL SSIIAIAVCG 300
  301 MLMKQYIKGN ITEAATNSVK YFTKMLAQCS ETVIFMFLGL STLTSEHHVD FIFIGATLVF 360
  361 CLIYRAIGII VQCFILNKFR AKKFEVVDQF ILSYGGLRGA IAYGLVVSIP ASIQAKPMFI 420
  421 TTTICVIYFT VFLQGITIRP LVNCLNVKKK EHREATMVES VYNKYLDYMM SGVEDIAGQR 480
  481 GHYSFIENFE RFNAKVIKPV LMRHEKRQSF DATSIIRAYE KITLEDAIKL TKVKSTLQNK 540
  541 RLEKVKSEVR VAPEQTTVTP KDVQLARFMQ SGENIDQLYT LFSDLLDKKL NELKVQADKV 600
  601 DKANDDDIQD DYMAEMGSHS NLGFMHHSAD QLDSDSVFQR RGRRLSTGDL KGHCGTSRKP 660
  661 KHSMFELRHV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..290] MSA 10.068996 View MSA. No confident structure predictions are available.
    2 View Details [291..447] MSA 4.057996 View MSA. No confident structure predictions are available.
    3 View Details [448..670] PSI-BLAST 3.69897 No description for 2i1jA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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