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Protein Overview: nhx-5

General Information:
Name(s) found: nhx-5 / CE31014 [WormBase]
Description(s) found:
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  • WBGene00003733 locus:nhx-5 Sodium\/hydrogen exchanger status:Confirmed UniProt:G5ED88 protein_id:CAA93476.2 [WormBase]
  • gi|71992101|ref|NP_001024720.1| Na/H eXchanger family member (nhx-5) [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_741891.1| Na/H eXchanger (70.3 kD) (nhx-5) [Caenorhabditis elegans] [NCBI NR]
  • gi|21615478|emb|CAA93476.2| C. elegans protein F57C7.2a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|20269924|gb|AAM18106.1|AF497828_1 putative Na-H exchanger isoform 5a [Caenorhabditis elegans] [NCBI NR]
  • [wormpep88.fasta]
  • CE31014 WBGene00003733 locus:nhx-5 Na(+)\/H(+) exchanger status:Confirmed TR:Q20944 protein_id:CAA93476.2 [wormpep150.fasta]
  • 31014 WBGene00003733 locus:nhx-5 Na(+)\/H(+) exchanger status:Confirmed TR:Q20944 protein_id:CAA93476.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • Na/H eXchanger (70.3 kD) (nhx-5) [Caenorhabditis elegans]gi|20269924|gb|AAM18106.1| putative Na-H exchanger isoform 5a [Caenorhabditis elegans]gi|21615478|emb|CAA93476.2| Hypothetical protein F57C7.2a [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:nhx-5 Na(+)\/H(+) exchanger status:Confirmed TR:Q20944 protein_id:CAA93476.2 [wormpep115.fasta.reversed]
  • CE31014 WBGene00003733 locus:nhx-5 Na(+)\/H(+) exchanger status:Confirmed UniProt:Q20944_CAEEL protein_id:CAA93476.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE31014 WBGene00003733 locus:nhx-5 Na(+)\/H(+) exchanger status:Confirmed UniProt:Q20944_CAEEL protein_id:CAA93476.2| [wormORF-contam.fasta]
  • Na/H eXchanger family member (nhx-5) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein F57C7.2a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • putative Na-H exchanger isoform 5a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE31014 WBGene00003733 locus:nhx-5 Na(+)\/H(+) exchanger status:Confirmed UniProt:Q20944 protein_id:CAA93476.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE31014 WBGene00003733 locus:nhx-5 Na(+)\/H(+) exchanger status:Confirmed UniProt:G5ED88 protein_id:CAA93476.2 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE31014 WBGene00003733 locus:nhx-5 status:Confirmed UniProt:G5ED88 protein_id:CAA93476.2 Sodium\/hydrogen exchanger [wormpep246-ecoli-contam.fasta]
  • Sodium/hydrogen exchanger OS=Caenorhabditis elegans GN=nhx-5 PE=2 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 630 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: sodium ion transport [IEALink to PubMed article]
    regulation of pH [IEALink to PubMed article]
    Molecular Function: solute:hydrogen antiporter activity [IEALink to PubMed article]
    sodium:hydrogen antiporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLLWTISTI LLISSTVAGS NNGNTRLDMA AQRRASNIHR MDTIILLTYV SVMVLIVVTA  60
   61 WAFKHYRFRF IHESGVTLFY GLLIGFVIRY FGLGLLQSQT FDVITKNKTI VKEPPDYLML 120
  121 EVKPEGGSRV SFHYELIEGF FADKRKKIEQ QIEQKSVFSP EVFFNMLIPP IIFNAGYSLK 180
  181 KRHFFRNIGS ILAIVFIGTT ISCFGTGCLM FVFTSIFQMG YSFKELLFFG ALISATDPVT 240
  241 IISVFNDMNV EADLFALIFG ESALNDAVAI VLSEVIENFS TSSEAITLQD FGSAIAGFAG 300
  301 VFFGSLMLGF MIGCMNAFLT KMTLISEHAL LESSLFVLIS YISFLVAEVC GLTGIVSVLF 360
  361 CGIAQAHYTY NNLSDESQSN TKHFFHMVSF IMESFIFCYI GVSVFVTNNQ RWSFSFLLFS 420
  421 LISITASRAL FVYPLSWLLN IRRRPKIPKR YQHMILFAGL RGAMAFALAG RNTSTENRQM 480
  481 IFATTTAVVI VTVLVNGGLT SWMIDYLQIK HGKDAIEEGQ RLENSMSSSP ADQHSDLDES 540
  541 VPVTMSPGLN PWDKAFLPRK WYHFDASFMK PLLTHATPSL EQTLPPFCLP LTSLLTSSRQ 600
  601 RAYVSAEPFN TIVQSGIPLI DGSGCDEESV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..100] MSA 1.853986 View MSA. No confident structure predictions are available.
    2 View Details [101..285] MSA 8.992995 View MSA. No confident structure predictions are available.
    3 View Details [286..511] MSA 5.986994 View MSA. No confident structure predictions are available.
    4 View Details [512..630] MSA 2.28699 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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