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Protein Overview: ercc-1

General Information:
Name(s) found: ercc-1 / CE30750 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00008665 locus:ercc-1 status:Confirmed UniProt:Q93456 protein_id:CAB02283.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 262 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    intracellular [IEALink to PubMed article]
    Biological Process: DNA repair [IEALink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    endonuclease activity [IEALink to PubMed article]
    damaged DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKHTEESLMS TTEKSRKAEE DDEKDMKKRT QFPSSSTSSD PPVGIGGSGA LVVNRRRQEG  60
   61 NPVLKYVRNV RYEWGDIGPD FECGPTFGVV YLSFKYHKQH PEYVYTRING NAENRYRNKV 120
  121 LLGYCNMEEP RHVLRELNMI CFREAWTFVV VYTVEEAAEY IELFKTTQKK EITIKKKAID 180
  181 DGGDSSMSDE RRRNREAAIG FLTAARSITK TDADRLLFHF GTLQAISTAS ETSISACPGV 240
  241 GPIKAKNLHS FLHAIISPNE QD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..179] PSI-BLAST 22.09691 Crystal Structure of the Central Domain of Human ERCC1
    2 View Details [180..262] PSI-BLAST 14.39794 Crystal Structure of the Complex between the C-Terminal Domains of Human XPF and ERCC1


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle