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Protein Overview: CE31291

General Information:
Name(s) found: CE31291 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00015512 locus:mthf-1 Methylenetetrahydrofolate reductase status:Confirmed UniProt:G8JXY2 protein_id:CCD61459.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 642 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: methionine biosynthetic process [IEALink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    methionine metabolic process [IEALink to PubMed article]
    Molecular Function: methylenetetrahydrofolate reductase (NADPH) activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVLSKNGVE TDENAVVEEK ITLESGKSWS PKHYELLHER IERLIDEKQQ FFSLEFFPPR  60
   61 FVNGVPNFLE RVERLSEGGS VFVDMTWHMG SDPANVDKVT SSSSIAASML DYCGVDTMLH 120
  121 MTCVQYNKAD TLKHLEQAKA MGLRSILALR GDLPPGTELE DTHQFRALDM IRWIREEYGN 180
  181 YFSIGCAGYP LGHPQAPSYK ADLMYLKAKC DAGANFVITQ LFFEAETFEK FVRDCREIGI 240
  241 TQPIIPGIMP IMGYESIKRI AKLSQLEIPQ HILDDLEPIK HDDDAVQKYG TERCIEMCRR 300
  301 LLDNGTAPSI HLYTMNREGS IREILKSLGL WKLEGDRVFP WKNRSQHPIR CLESVRPIYW 360
  361 SFRPRSYITR TRDWDQFPNG RWGNSSSPAF GDVSSYYLSN LTTVRNADDR LAMFGANIES 420
  421 FEDVKRVFIN YITQAPNADG VKVTVLPWTE AETGVQPETS LISEQLVWCN ENGILTVNSQ 480
  481 PSVNGAPSTD PLVGWGKPGG YCYQKAYLEC FMTAELSDKL IQIIEREFPV RVNYHAINKD 540
  541 STFDKTNSEE TTPIAVTWGV FPGSEIAQPT VVDPLSFRAW RDEAYQMWMA QWGDFYPKES 600
  601 KSYGVIKAVH DEFRLVTLVD NDFQKPSVLF DVLQKALDEL KK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..334] PSI-BLAST 98.39794 E. coli Methylenetetrahydrofolate Reductase (oxidized)
    2 View Details [335..497] deduced N/A No confident structure predictions are available.
    3 View Details [498..642] MSA 2.029953 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle