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Protein Overview: mmcm-1

General Information:
Name(s) found: mmcm-1 / CE30404 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00014202 locus:mmcm-1 Probable methylmalonyl-CoA mutase, mitochondrial status:Confirmed UniProt:Q23381 protein_id:CAA84676.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 744 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: metabolic process [IEALink to PubMed article]
    lactate fermentation to propionate and acetate [IEALink to PubMed article]
    Molecular Function: intramolecular transferase activity [IEALink to PubMed article]
    metal ion binding [IEALink to PubMed article]
    cobalamin binding [IEALink to PubMed article]
    methylmalonyl-CoA mutase activity [IEALink to PubMed article]
    isomerase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYLQLLKPTL LRCSTRPSSS GAYTRSPIDQ KWAAMAKKAM KGREADTLTW NTPEGIPIKP  60
   61 LYLRSDRDCD AQRSVELPGQ FPFTRGPYPT MYTQRPWTIR QYAGFSTVEE SNKFYKENIK 120
  121 AGQQGLSVAF DLATHRGYDS DNPRVFGDVG MAGVAVDSVE DMRQLFDGIN LEKMSVSMTM 180
  181 NGAVVPVLAM YVVAAEEAGV SRKLLAGTIQ NDILKEFMVR NTYIYPPEPS MRIIGDIFAY 240
  241 TSREMPKFNS ISISGYHMQE AGADAVLEMA FTIADGIQYC ETGLNAGLTI DAFAPRLSFF 300
  301 WGISMNFYME IAKMRAARRL WANLIKERFS PKSDKSMMLR THSQTSGWSL TEQDPYNNII 360
  361 RTTIEAMASV FGGTQSLHTN SFDEALGLPT KFSARIARNT QIIIQEESGI CNVADPWGGS 420
  421 YMMESLTDEI YEKALAVIKE IDELGGMAKA VASGMTKLKI EEAAAKKQAR IDAGKDVIVG 480
  481 VNKYRLDHEQ QVEVLKIDNA KVREEQCAKL NHIRATRDAE KAQKALDAIT EGARGNGNLM 540
  541 ELAIEAARAR CTVGEISDAM EKVFNRHAAV NRLVSGAYKS EFGETSEMSQ VLERVKSFAD 600
  601 RDGRQPRIMV AKMGQDGHDR GAKVIATGFA DLGFDVDVGP LFQTPLEAAQ QAVDADVHVI 660
  661 GASSLAAGHL TLIPQLIGEL KKLGRPDILV VAGGVIPPQD YKELYDAGVA LVFGPGTRLP 720
  721 ACANQILEKL EANLPEAPGK AASR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..744] PSI-BLAST 1000.0 Methylmalonyl-CoA mutase alpha subunit, domain 1; Methylmalonyl-CoA mutase alpha subunit, C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • methylmalonyl-CoA mutase activity
    		•  5.02968768984763 bayes_pls_golite062009
  • binding
    		•  1.2054430376474 bayes_pls_golite062009
  • protein binding
    		•  0.657913936613888 bayes_pls_golite062009
  • catalytic activity
    		•  0.424959044318554 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.76

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle