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Protein Overview: atm-1

General Information:
Name(s) found: atm-1 / CE30018 [WormBase]
Description(s) found:
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  • WBGene00000227 locus:atm-1 status:Partially_confirmed UniProt:Q9N3Q4 protein_id:CCD72872.1 [WormBase]
  • gi|25145564|ref|NP_490693.2| ATM (ataxia telangectasia mutated) family member (atm-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|16950490|gb|AAF60692.2| Atm (ataxia telangectasia mutated) family protein 1 [Caenorhabditis elegans] [NCBI NR]
  • Serine/threonine-protein kinase ATM OS=Caenorhabditis elegans GN=atm-1 PE=3 SV=2 [Swiss-Prot]
  • [wormpep79.fasta]
  • CE30018 WBGene00000227 locus:atm-1 status:Partially_confirmed TR:Q9N3Q4 protein_id:AAF60692.2 [wormpep150.fasta]
  • 30018 WBGene00000227 locus:atm-1 status:Partially_confirmed TR:Q9N3Q4 protein_id:AAF60692.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • ataxia Telangectasia Mutated related (atm-1) [Caenorhabditis elegans]gi|16950490|gb|AAF60692.2| Atm (ataxia telangectasia mutated) family protein 1 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:atm-1 status:Partially_confirmed TR:Q9N3Q4 protein_id:AAF60692.2 [wormpep115.fasta.reversed]
  • CE30018 status:Partially_confirmed TR:Q9N3Q4 protein_id:AAF60692.2 [wormpep80.hongbin]
  • CE30018 WBGene00000227 locus:atm-1 status:Partially_confirmed UniProt:Q9N3Q4_CAEEL protein_id:AAF60692.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE30018 WBGene00000227 locus:atm-1 status:Partially_confirmed UniProt:Q9N3Q4_CAEEL protein_id:AAF60692.2| [wormORF-contam.fasta]
  • ATM (ataxia telangectasia mutated) family member (atm-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Atm (ataxia telangectasia mutated) family protein 1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE30018 WBGene00000227 locus:atm-1 status:Partially_confirmed UniProt:Q9N3Q4 protein_id:AAF60692.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • CE30018 WBGene00000227 locus:atm-1 status:Partially_confirmed UniProt:Q9N3Q4 protein_id:CCD72872.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
    • Organism: Caenorhabditis elegans
    Length: 649 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: phosphotransferase activity, alcohol group as acceptor [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKHYKKIIHQ VLLKLHSVCI GQLSKLEEYR ETRTYRMKQQ AVTAFEQQIQ NSCRTSLARG  60
   61 NSGDEWTKKT VQRVRKEHQF EKNDLEKVDN SLNSAARKAV SSGFDALLCI SQLEDDDEAI 120
  121 RASSLIIFPL IDVIYKYETD VGVIALLKEH TKSKLPSKLW ISATSHIASK CFSIEKSQIT 180
  181 RHLSQILCHL IYDYPYHVLH TILMYDDEKN ASKVKGFLKT IFDARADQRD SSKLKEIVIT 240
  241 IREAHQAYRE IAMLDVRGNV RIQRVEINGK TMYRWPHDLK IFKCKLRQLP IPTISQKIGC 300
  301 PGDYSTTDLI TWKRWKDVFT IADGISTPKI WEIEGSDGKW YKTVWKKDDV RQDVLVEQMF 360
  361 DVTNNMLEKA MLRTYNVVPL DTECGVIEFC GGTVSLKEVM CGVTREGGLH REFNSEEVSA 420
  421 SKVSSMMRQV QTESTETRRQ VFVEICQQYS PVFRHFFYTN FSTAQIWRQK IINYRQSLAT 480
  481 WSIVCYIVGL GDRHASNILF DQKLCTFVHI DLGMILEYSK RTLPVPEQVP FRITRDVLDP 540
  541 ILIEGIENGQ LAEECTQIME KLKENGKVIL GVASALLRET MTNFREAEQA AGRPSYISEM 600
  601 AIGRLREKLR GTDDGVTAQS SNLQIRRLLR EATSADNLSR MFCGWMPFL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..649] PSI-BLAST 87.221849 Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.686492203566958 bayes_pls_golite062009
  • transferase activity
    		•  0.66841261245817 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.66326000691279 bayes_pls_golite062009
  • kinase activity
    		•  0.65753777854807 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.64444215862273 bayes_pls_golite062009
  • protein kinase activity
    		•  0.56587465829201 bayes_pls_golite062009
  • binding
    		•  0.0554152720226 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle