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Protein Overview: sams-5

General Information:
Name(s) found: sams-5 / CE30175 [WormBase]
Description(s) found:
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  • WBGene00006416 locus:sams-5 Probable S-adenosylmethionine synthase 5 status:Confirmed UniProt:Q27522 protein_id:CCD72063.1 [WormBase]
  • gi|26454642|sp|Q27522.2|METK5_CAEEL RecName: Full=Probable S-adenosylmethionine synthetase 5; Short=AdoMet synthetase 5; AltName: Full=Methionine adenosyltransferase 5; Short=MAT 5 [NCBI NR]
  • gi|25145633|ref|NP_741415.1| Temporarily Assigned Gene name family member (tag-32) [Caenorhabditis elegans] [NCBI NR]
  • gi|21106027|gb|AAB38126.2| Temporarily assigned gene name protein 32, isoform a [Caenorhabditis elegans] [NCBI NR]
  • Probable S-adenosylmethionine synthetase tag-32 (EC 2.5.1.6) (Methionine adenosyltransferase) (AdoMet synthetase) - Caenorhabditis elegans [Swiss-Prot]
  • Probable S-adenosylmethionine synthase 5 OS=Caenorhabditis elegans GN=sams-5 PE=3 SV=2 [Swiss-Prot]
  • Probable S-adenosylmethionine synthetase tag-32 OS=Caenorhabditis elegans GN=tag-32 PE=2 SV=2 [Swiss-Prot]
  • [wormpep79.fasta]
  • CE30175 WBGene00006416 locus:tag-32 S-adenosylmethionine synthetase status:Confirmed SW:Q27522 protein_id:AAB38126.2 [wormpep150.fasta]
  • 30175 WBGene00006416 locus:tag-32 S-adenosylmethionine synthetase status:Confirmed SW:Q27522 protein_id:AAB38126.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • methionine adenosyltransferase family member (4H42) [Caenorhabditis elegans]gi|21106027|gb|AAB38126.2| Temporarily assigned gene name protein 32, isoform a [Caenorhabditis elegans]gi|26454642|sp|Q27522|METN_CAEEL Probable S-adenosylmethionine synthetase [nrdb_11152004_Chlamydomonas]
  • S-adenosylmethionine synthetase status:Partially_confirmed SW:Q27522 protein_id:AAB38126.2 [wormpep115.fasta.reversed]
  • CE30175 S-adenosylmethionine synthetase status:Partially_confirmed SW:Q27522 protein_id:AAB38126.2 [wormpep80.hongbin]
  • CE30175 WBGene00006416 locus:tag-32 S-adenosylmethionine synthetase status:Confirmed UniProt:Q27522 protein_id:AAB38126.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE30175 WBGene00006416 locus:tag-32 S-adenosylmethionine synthetase status:Confirmed UniProt:Q27522 protein_id:AAB38126.2| [wormORF-contam.fasta]
  • Temporarily assigned gene name protein 32, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Temporarily Assigned Gene name family member (tag-32) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Probable S-adenosylmethionine synthetase tag-32 (Methionine adenosyltransferase) (AdoMet synthetase) [nr-271106-contam.fasta]
  • CE30175 WBGene00006416 locus:sams-5 S-adenosylmethionine synthetase status:Confirmed UniProt:Q27522 protein_id:AAB38126.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE30175 WBGene00006416 locus:sams-5 S-adenosylmethionine synthetase status:Confirmed UniProt:Q27522 protein_id:CCD72063.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE30175 WBGene00006416 locus:sams-5 status:Confirmed UniProt:Q27522 protein_id:CCD72063.1 Probable S-adenosylmethionine synthase 5 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 404 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    one-carbon metabolic process [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    methionine adenosyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKNKFLFTS ESVSEGHPDK MCDQISDAVL DAHLAQDPHA KVACETVTKT GMIMLCGEIT  60
   61 SKAVVDYQVL VRNVIKKIGY DDSSKGFDYK TCNVLVALEQ QSPEIAAGVH VDKDIADVGA 120
  121 GDQGIMFGYA TDETEEAMPL TLLLSHKLNY KLHELRRSGE LEWVRPDSKT QVTIEYSSEG 180
  181 GACVPLRVHT VVISTQHSPD ISLEDLRKEL IEKVIKVVIP GNLIDNDTVY HLNPCGSFVV 240
  241 GGPMGDAGLT GRKIIVDTYG GWGAHGGGAF SGKDPTKVDR SAAYAARWVA KSLVKAGLCR 300
  301 RCLVQVSYAI GVAKPLSVMV FSFGTSALNE AELLKIVNDN FDLRPGMIIK NLDLKRAIYE 360
  361 PTAENGHFGH NDFPWEQARK LKIDKDLRAK SKGPALVDAI GIAH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..404] PSI-BLAST 1000.0 No description for 2p02A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • methionine adenosyltransferase activity
    		•  8.00759843092519 bayes_pls_golite062009
  • transferase activity
    		•  1.78879119839291 bayes_pls_golite062009
  • binding
    		•  1.70779292877479 bayes_pls_golite062009
  • catalytic activity
    		•  1.59111295908728 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  1.11999094477144 bayes_pls_golite062009
  • protein binding
    		•  0.298204436433395 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle