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Protein Overview: ptb-1

General Information:
Name(s) found: ptb-1 / CE30509 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00004207 locus:ptb-1 status:Confirmed UniProt:Q8T3E6 protein_id:CAD30435.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 453 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: mRNA processing [IEALink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAPQVLTSD HPYHQHDVVF RTAVVPAAPV NNNDVVVGAA STGRAAGKSV ANGSVSNFEV  60
   61 GTQQQPNSVL RTIIENMMFP VSLDVLYQLF TRYGKVLRII TFNKNNTFQA LVQMSEANSA 120
  121 QLAKQGLENQ NVYNGCCTLR IDYSKLSTLN VKYNNDKSRD YTNPNLPAGE MTLEQTIAMS 180
  181 IPGLQNLIPA NPYNFAFGAN PATTFLTTQL AASTAAAAAV NDSANAAALA PYLNPLGLTS 240
  241 ANLAPSISSM RFPMINLTPV ILVSNLHEMK VTTDALFTLF GVYGDVMRVK ILYNKKDNAL 300
  301 IQYSEPQQAQ LALTHLDKVK WHDRLIRVAP SKHTNVQMPK EGQPDAGLTR DYAHSTLHRF 360
  361 KKPGSKNYLN IYPPCATLHL SNIPTSVSEE KLKEMFAEAG FAVKAFKFFP KDHKMALCQL 420
  421 EDIETAIDAL IAMHNHKLAE NAHLRVSFSK SGI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..246] PSI-BLAST 24.39794 NMR Structure of RRM2 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1)
    2 View Details [247..453] PSI-BLAST 42.522879 Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.38904784081546 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.535128751388028 bayes_pls_golite062009
  • RNA binding
    		•  0.423111514770653 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  1.38904784081546 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.535128751388028 bayes_pls_golite062009
  • RNA binding
    		•  0.423111514770653 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle