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Protein Overview: CE30593

General Information:
Name(s) found: CE30593 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00015512 locus:mthf-1 Probable methylenetetrahydrofolate reductase status:Confirmed UniProt:Q17693 protein_id:CCD61458.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 663 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: methionine biosynthetic process [IEALink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    methionine metabolic process [IEALink to PubMed article]
    Molecular Function: methylenetetrahydrofolate reductase (NADPH) activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNTGETKVI ESHGTIKKID SLSTMPYCGV ETDENAVVEE KITLESGKSW SPKHYELLHE  60
   61 RIERLIDEKQ QFFSLEFFPP RFVNGVPNFL ERVERLSEGG SVFVDMTWHM GSDPANVDKV 120
  121 TSSSSIAASM LDYCGVDTML HMTCVQYNKA DTLKHLEQAK AMGLRSILAL RGDLPPGTEL 180
  181 EDTHQFRALD MIRWIREEYG NYFSIGCAGY PLGHPQAPSY KADLMYLKAK CDAGANFVIT 240
  241 QLFFEAETFE KFVRDCREIG ITQPIIPGIM PIMGYESIKR IAKLSQLEIP QHILDDLEPI 300
  301 KHDDDAVQKY GTERCIEMCR RLLDNGTAPS IHLYTMNREG SIREILKSLG LWKLEGDRVF 360
  361 PWKNRSQHPI RCLESVRPIY WSFRPRSYIT RTRDWDQFPN GRWGNSSSPA FGDVSSYYLS 420
  421 NLTTVRNADD RLAMFGANIE SFEDVKRVFI NYITQAPNAD GVKVTVLPWT EAETGVQPET 480
  481 SLISEQLVWC NENGILTVNS QPSVNGAPST DPLVGWGKPG GYCYQKAYLE CFMTAELSDK 540
  541 LIQIIEREFP VRVNYHAINK DSTFDKTNSE ETTPIAVTWG VFPGSEIAQP TVVDPLSFRA 600
  601 WRDEAYQMWM AQWGDFYPKE SKSYGVIKAV HDEFRLVTLV DNDFQKPSVL FDVLQKALDE 660
  661 LKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..353] PSI-BLAST 97.69897 E. coli Methylenetetrahydrofolate Reductase (oxidized)
    2 View Details [354..518] deduced N/A No confident structure predictions are available.
    3 View Details [519..663] MSA 2.029953 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle