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Protein Overview: CE29208

General Information:
Name(s) found: CE29208 [WormBase]
Description(s) found:
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  • WBGene00016335 locus:gba-1 Putative glucosylceramidase 1 status:Confirmed UniProt:O16580 protein_id:CCD66449.1 [WormBase]
  • gi|17532261|ref|NP_494207.1| C33C12.3 [Caenorhabditis elegans] [NCBI NR]
  • gi|15617722|gb|AAB66056.2| Hypothetical protein C33C12.3a [Caenorhabditis elegans] [NCBI NR]
  • gi|115532470|ref|NP_001040750.1| hypothetical protein C33C12.3 [Caenorhabditis elegans] [NCBI NR]
  • Putative glucosylceramidase 1 OS=Caenorhabditis elegans GN=gba-1 PE=1 SV=2 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE29208 WBGene00016335 glucosylceramidase status:Partially_confirmed TR:O16580 protein_id:AAB66056.2 [wormpep150.fasta]
  • 29208 WBGene00016335 glucosylceramidase status:Partially_confirmed TR:O16580 protein_id:AAB66056.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • glucocerebrosidase precursor family member (58.2 kD) (2C471) [Caenorhabditis elegans]gi|15617722|gb|AAB66056.2| Hypothetical protein C33C12.3 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • glucosylceramidase status:Partially_confirmed TR:O16580 protein_id:AAB66056.2 [wormpep115.fasta.reversed]
  • CE29208 glucosylceramidase status:Partially_confirmed TR:O16580 protein_id:AAB66056.2 [wormpep80.hongbin]
  • CE29208 WBGene00016335 glucosylceramidase status:Partially_confirmed UniProt:O16580_CAEEL protein_id:AAB66056.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE29208 WBGene00016335 glucosylceramidase status:Partially_confirmed UniProt:O16580_CAEEL protein_id:AAB66056.2| [wormORF-contam.fasta]
  • CE29208 WBGene00016335 glucosylceramidase status:Partially_confirmed [wormpep160-contam.fasta]
  • C33C12.3a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein C33C12.3 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE29208 WBGene00016335 glucosylceramidase status:Partially_confirmed UniProt:O16580 protein_id:AAB66056.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE29208 WBGene00016335 locus:gba-1 glucosylceramidase status:Confirmed UniProt:O16580 protein_id:CCD66449.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE29208 WBGene00016335 locus:gba-1 status:Confirmed UniProt:O16580 protein_id:CCD66449.1 Putative glucosylceramidase 1 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 523 amino acids

    Gene Ontology:
    Cellular Component: lysosome [IEALink to PubMed article]
    Biological Process: lysosome organization [IEALink to PubMed article]
    sphingolipid metabolic process [IEALink to PubMed article]
    Molecular Function: glucosylceramidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSRFLLKIF IFLAVFGVDS VRAADCTEKT FKTGTVCVCS LDSCDEIPPL DITMGQAALY  60
   61 TTSHTGARLH RDVIYATDTE PFGTLHMTID SSKKYQTIQG FGSTFSDASG ANLKSLPDKL 120
  121 SDLIMKQYFS DTGLNLQFGR VPIASTDFSG RVYSYNDVAN DYSMQNFNLT KEDFQWKIPY 180
  181 IKNAQKYNPN LKLFAAPWAA PGWLKTTKEM TGPGALNGKA GDNYHQAYAK YFVRFLEEYG 240
  241 KSGISFWGLS TQNQPTLGSD KKNKIQSTLF TAETQRDFIK TDLGPALAAS SSGKDVKLLI 300
  301 LDDNRGNLPK WADTVLNDMD AAKYVGGIGV HAYQDGETDN HLDETHKKHP NFFILGTEAS 360
  361 EGYGSKDTHV DYGNWDRAAD TASDILDNMN NWMTGWTERN LILDALGGPS WVSDYTDAPV 420
  421 IAFPAMAQFY KQPMFYAIAH FSHFIKPGAV RIDHSLNVIE LEVETTAFLN PDGSKVIVML 480
  481 NKGSLVSTEH TVVVQDAADS RNHYHFTLPH RAITTLYIQT SQF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..523] PSI-BLAST 155.0 No description for 2v3dA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  4.11319792356479 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  3.92012282533754 bayes_pls_golite062009
  • chitinase activity
    		•  2.45357334610104 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • hydrolase activity
    		•  1.54366929433155 bayes_pls_golite062009
  • amylase activity
    		•  0.748967897302847 bayes_pls_golite062009
  • glucosidase activity
    		•  0.528679164808812 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.4998423581103 bayes_pls_golite062009
  • hexosaminidase activity
    		•  0.423006654245821 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle