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Protein Overview: unc-101

General Information:
Name(s) found: unc-101 / CE28050 [WormBase]
Description(s) found:
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  • WBGene00006829 locus:unc-101 AP-1 complex subunit mu-1-I status:Confirmed UniProt:P35602 protein_id:CAB05557.3 [WormBase]
  • gi|21542385|sp|P35602.2|AP1M_CAEEL RecName: Full=AP-1 complex subunit mu-1-I; AltName: Full=Mu1-I-adaptin; AltName: Full=Golgi adaptor AP-1 47 kDa protein; AltName: Full=HA1 47 kDa subunit; AltName: Full=Clathrin assembly protein complex 1 medium chain; A [NCBI NR]
  • gi|17508211|ref|NP_493174.1| UNCoordinated family member (unc-101) [Caenorhabditis elegans] [NCBI NR]
  • gi|14530511|emb|CAB05557.3| C. elegans protein K11D2.3a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|115532320|ref|NP_001040675.1| UNCoordinated family member (unc-101) [Caenorhabditis elegans] [NCBI NR]
  • (P35602) Clathrin coat assembly protein AP47 (Clathrin coat associated protein AP47) (Golgi adaptor AP-1 47 kDa protein) (HA1 47 kDa subunit) (Clathrin assembly protein assembly protein complex 1 medium chain) (Uncoordinated protein 101) [Swiss-Prot]
  • AP-1 complex subunit mu-1-I OS=Caenorhabditis elegans GN=unc-101 PE=2 SV=2 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE28050 WBGene00006829 locus:unc-101 clathrin coat assembly protein status:Confirmed SW:P35602 protein_id:CAB05557.3 [wormpep150.fasta]
  • 28050 WBGene00006829 locus:unc-101 clathrin coat assembly protein status:Confirmed SW:P35602 protein_id:CAB05557.3 [wormpep130-phg-ecoli-orf-rand.fasta]
  • UNCoordinated locomotion UNC-101, adaptor (48.2 kD) (unc-101) [Caenorhabditis elegans]gi|14530511|emb|CAB05557.3| Hypothetical protein K11D2.3 [Caenorhabditis elegans]gi|21542385|sp|P35602|AP47_CAEEL Clathrin coat assembly protein AP47 (Clathrin coat as [nrdb_11152004_Chlamydomonas]
  • locus:unc-101 clathrin coat assembly protein status:Confirmed SW:P35602 protein_id:CAB05557.3 [wormpep115.fasta.reversed]
  • CE28050 locus:unc-101 clathrin coat assembly protein status:Confirmed TR:O02282 protein_id:CAB05557.3 [wormpep80.hongbin]
  • CE28050 WBGene00006829 locus:unc-101 clathrin coat assembly protein status:Confirmed UniProt:P35602 protein_id:CAB05557.3 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE28050 WBGene00006829 locus:unc-101 clathrin coat assembly protein status:Confirmed UniProt:P35602 protein_id:CAB05557.3| [wormORF-contam.fasta]
  • Hypothetical protein K11D2.3a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • AP-1 complex subunit mu (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor AP-1 47 kDa protein) (HA1 47 kDa subunit) (Clathrin assembly protein assembly protein complex 1 medium chain) (Uncoordinated protein 101) [nr-271106-contam.fasta]
  • UNCoordinated family member (unc-101) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE28050 WBGene00006829 locus:unc-101 status:Confirmed UniProt:P35602 protein_id:CAB05557.3 AP-1 complex subunit mu-1-I [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 422 amino acids

    Gene Ontology:
    Cellular Component: membrane coat [IEALink to PubMed article]
    clathrin adaptor complex [IEALink to PubMed article]
    Biological Process: vesicle-mediated transport [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    protein complex assembly [IEALink to PubMed article]
    intracellular protein transport [IEALink to PubMed article]
    Molecular Function: protein binding [IEALink to PubMed article]
    protein transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATSAMFILD LKGKTIISRN YRGDIDMTAI DKFIHLLMEK EEEGSAAPVL TYQDTNFVFI  60
   61 KHTNIYLVSA CRSNVNVTMI LSFLYKCVEV FSEYFKDVEE ESVRDNFVVI YELLDEMMDF 120
  121 GFPQTTESRI LQEYITQEGQ KLISAPRPPM AVTNAVSWRS EGIKYRKNEV FLDVIESVNM 180
  181 LASANGTVLQ SEIVGSVKMR VYLTGMPELR LGLNDKVLFE GSGRGKSKSV ELEDVKFHQC 240
  241 VRLSRFDTDR TISFIPPDGA FELMSYRLTT VVKPLIWIET SIERHSHSRV SFIIKAKSQF 300
  301 KRRSTANNVE IIIPVPSDAD SPKFKTSIGS VKYTPEQSAF VWTIKNFPGG KEYLLTAHLS 360
  361 LPSVMSEESE GRPPIKVKFE IPYFTTSGIQ VRYLKIIEKS GYQALPWVRY ITQNGEYEMR 420
  421 MK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..422] PSI-BLAST 133.0 AP1 clathrin adaptor core


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle