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Protein Overview: klc-2

General Information:
Name(s) found: klc-2 / CE27362 [WormBase]
Description(s) found:
Found 16 descriptions.
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  • WBGene00002215 locus:klc-2 Kinesin light chain status:Confirmed UniProt:P46822 protein_id:CCD65110.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 522 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: synaptic vesicle transport [IPI]
    locomotion [IMP]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    oviposition [IMP]
    Molecular Function: microtubule motor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLAGSTIQA YRQRKIESLA KMSNMSQDDV TTGLRTVQQG LEALREEHST ISNTLETSVK  60
   61 GVKEDEAPLP KQKLSQINDN LDKLVCGVDE TSLMLMVFQL TQGMDAQHQK YQAQRRRLCQ 120
  121 ENAWLRDELS STQIKLQQSE QMVAQLEEEN KHLKYMASIK QFDDGTQSDT KTSVDVGPQP 180
  181 VTNETLQELG FGPEDEEDMN ASQFNQPTPA NQMAASANVG YEIPARLRTL HNLVIQYASQ 240
  241 GRYEVAVPLC KQALEDLEKT SGHDHPDVAT MLNILALVYR DQNKYKEAAN LLNEALSIRE 300
  301 KCLGESHPAV AATLNNLAVL FGKRGKFKDA EPLCKRALEI REKVLGDDHP DVAKQLNNLA 360
  361 LLCQNQGKYE EVEKYYKRAL EIYESKLGPD DPNVAKTKNN LSSAYLKQGK YKEAEELYKQ 420
  421 ILTRAHEREF GQISGENKPI WQIAEEREEN KHKGEGATAN EQAGWAKAAK VDSPTVTTTL 480
  481 KNLGALYRRQ GKYEAAETLE DVALRAKKQM SESRRMERSV MY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run knl-1 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135] PSI-BLAST 14.30103 No description for 2j9qA was found.
    2 View Details [136..522] PSI-BLAST 38.30103 The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.14253214573541 bayes_pls_golite062009
  • protein binding
    		•  1.65083457326273 bayes_pls_golite062009
  • signal sequence binding
    		•  0.49295886046194 bayes_pls_golite062009
  • peroxisome targeting sequence binding
    		•  0.0468412220974996 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle