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Protein Overview: flr-1

General Information:
Name(s) found: flr-1 / CE27118 [WormBase]
Description(s) found:
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  • WBGene00001465 locus:flr-1 status:Confirmed UniProt:G5EGI5 protein_id:CAA91936.2 [WormBase]
  • pir||T37309 flr-1 protein - Caenorhabditis elegans [NCBI NR]
  • gi|3702222|dbj|BAA33488.1| FLR-1 [Caenorhabditis elegans] [NCBI NR]
  • gi|17568351|ref|NP_510243.1| FLuoRide resistant family member (flr-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|13548339|emb|CAA91936.2| C. elegans protein F02D10.5, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE27118 WBGene00001465 locus:flr-1 sodium channel like status:Confirmed TR:Q19115 protein_id:CAA91936.2 [wormpep150.fasta]
  • 27118 WBGene00001465 locus:flr-1 sodium channel like status:Confirmed TR:Q19115 protein_id:CAA91936.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • FLuoRide resistant FLR-1, ion channel similar to amiloride-sensitive sodium channel, modulates defecation rhythm, pace of development and fluoride sensitivity (72.3 kD) (flr-1) [Caenorhabditis elegans]gi|13548339|emb|CAA91936.2| Hypothetical protein F02D [nrdb_11152004_Chlamydomonas]
  • locus:flr-1 sodium channel like status:Confirmed TR:Q19115 protein_id:CAA91936.2 [wormpep115.fasta.reversed]
  • CE27118 locus:flr-1 sodium channel like status:Confirmed TR:Q19115 protein_id:CAA91936.2 [wormpep80.hongbin]
  • CE27118 WBGene00001465 locus:flr-1 sodium channel like status:Confirmed UniProt:Q19115_CAEEL protein_id:CAA91936.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE27118 WBGene00001465 locus:flr-1 sodium channel like status:Confirmed UniProt:Q19115_CAEEL protein_id:CAA91936.2| [wormORF-contam.fasta]
  • FLR-1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • FLuoRide resistant family member (flr-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein F02D10.5 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE27118 WBGene00001465 locus:flr-1 sodium channel like status:Confirmed UniProt:Q19115 protein_id:CAA91936.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE27118 WBGene00001465 locus:flr-1 sodium channel like status:Confirmed UniProt:G5EGI5 protein_id:CAA91936.2 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE27118 WBGene00001465 locus:flr-1 status:Confirmed UniProt:G5EGI5 protein_id:CAA91936.2 [wormpep246-ecoli-contam.fasta]
  • FLR-1 OS=Caenorhabditis elegans GN=flr-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 638 amino acids

    Gene Ontology:
    Cellular Component: membrane [IDALink to PubMed article][IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: sodium ion transport [IEALink to PubMed article][TASLink to PubMed article]
    ion transport [IEALink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    defecation [IMPLink to PubMed article]
    ultradian rhythm [IMPLink to PubMed article]
    Molecular Function: ion channel activity [IEALink to PubMed article]
    sodium channel activity [IEALink to PubMed article][ISSLink to PubMed article]
    amiloride-sensitive sodium channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METETESERI YLQLYDYETK EFSGLTTYHG LVRIYNSNTW PSRIFWVVVV LSCLSLFMIH  60
   61 SGYLLLGYHA KPTLFQTNTI VPMNGLLFPE VTICNLNPLN TTKLEELNIS KSTWTYIFGY 120
  121 FDEITTSEHK STKLGEEQFL EIMNNYQELT KQEFNVKNFL KSVSKSCEET FISCSFGREK 180
  181 LHNCCEHVTT EMTEVGVCFR LSNVNKKYRQ WYSGNGFGWE FVLNGNNEID DHADSLDFEP 240
  241 DRGFLIMVHE SEKYPKINSY GVAVSPDSQL HAAISMKNIS LLDKANWGSC SKGWNRNDTD 300
  301 VPYTATHCEI DCKLRKVRNL CGCSPLAYSA RESGSNDTIC TPYQIQQCFR KVRGLDNRWE 360
  361 DECDCPSECN MLEFDVTNSY SDLDGRSRGL SSSKVESDIS HVSLYFSHVA YERIEQQKQL 420
  421 QTADLLSNIA GSMGLFLGMS TVTLLEIFIY LFKSVWGTVN STRQQQFVDA VAEEEKERSE 480
  481 SIVIIQNGRN DDMDDQKPSR FPGADRKLSG NSIHIHLDRR NSRMIRGGDL SAASRGSVSI 540
  541 PSQLLSPLSR HNRQSISYGQ LGRKVSAIGI PLQPNHDTVE SGTSLMPPKS PIRRCSTSTT 600
  601 PSMLTRKLSF ASQQSDPAQP AHQSRKVSTS SIFKSQLI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..467] PSI-BLAST 109.0 No description for 2qtsA was found.
    2 View Details [468..638] MSA 51.126997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle