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Protein Overview: daf-28

General Information:
Name(s) found: daf-28 / CE25720 [WormBase]
Description(s) found:
Found 16 descriptions.
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  • WBGene00000920 locus:daf-28 status:Partially_confirmed UniProt:Q9NEK7 protein_id:CAB61047.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 97 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEALink to PubMed article][ISSLink to PubMed article]
    Biological Process: dauer larval development [IMPLink to PubMed article]
    response to external stimulus [IEPLink to PubMed article]
    regulation of transcription factor import into nucleus [IGILink to PubMed article]
    response to starvation [IEPLink to PubMed article]
    regulation of insulin receptor signaling pathway [IGILink to PubMed article]
    Molecular Function: insulin receptor binding [ISSLink to PubMed article]
    hormone activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNCKLIAIFA VLVLSVSAHL GAQAAAANFK AEGPLSRAVR VPGVAVRACG RRLVPYVWSV  60
   61 CGDACEPQEG IDIATQCCTY QCTAEYIQTA CCPRLLL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..97] FFAS03 1.32 Insulin-like growth factor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • insulin receptor binding
    		•  2.7278725657614 bayes_pls_golite062009
  • insulin-like growth factor receptor binding
    		•  2.52789753864303 bayes_pls_golite062009
  • receptor binding
    		•  1.96314913282044 bayes_pls_golite062009
  • binding
    		•  1.53606661868923 bayes_pls_golite062009
  • protein binding
    		•  1.03308976416246 bayes_pls_golite062009
  • growth factor activity
    		•  0.882616311405838 bayes_pls_golite062009
  • protein complex binding
    		•  0.391427446215436 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle