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Protein Overview: lag-1

General Information:
Name(s) found: lag-1 / CE25048 [WormBase]
Description(s) found:
Found 15 descriptions.
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  • WBGene00002245 locus:lag-1 status:Confirmed UniProt:Q8MXE7 protein_id:CCD72376.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 671 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: positive regulation of vulval development [IMPLink to PubMed article]
    collagen and cuticulin-based cuticle attachment to epithelium [IMPLink to PubMed article]
    molting cycle, protein-based cuticle [IMPLink to PubMed article]
    regulation of cell fate specification [IMPLink to PubMed articleLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    germ-line stem cell division [IMPLink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    cell fate specification [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLAYSTHDN FYESPKTPQP TWDHVHAQFP LGEPARNLDK FIEAMFQSVS PLAGVAAAPS  60
   61 QIAALQQIQA LMTFQMQQNN LFPKIDTISK SPTPELASPS AKRMRLSPST SSHSDVASTS 120
  121 KGTNGQDQSK NSPTNSDPFY TIGQSTPNTS SFLDTSNSSF GAPSTVVANP MTNYQLAFQA 180
  181 KLGSLHSLIG DSVQSLTSDR MIDFLSNKEK YECVISIFHA KVAQKSYGNE KRFFCPPPCI 240
  241 YLIGQGWKLK KDRVAQLYKT LKASAQKDAA IENDPIHEQQ ATELVAYIGI GSDTSERQQL 300
  301 DFSTGKVRHP GDQRQDPNIY DYCAAKTLYI SDSDKRKYFD LNAQFFYGCG MEIGGFVSQR 360
  361 IKVISKPSKK KQSMKNTDCK YLCIASGTKV ALFNRLRSQT VSTRYLHVEG NAFHASSTKW 420
  421 GAFTIHLFDD ERGLQETDNF AVRDGFVYYG SVVKLVDSVT GIALPRLRIR KVDKQQVILD 480
  481 ASCSEEPVSQ LHKCAFQMID NELVYLCLSH DKIIQHQATA INEHRHQIND GAAWTIISTD 540
  541 KAEYRFFEAM GQVANPISPC PVVGSLEVDG HGEASRVELH GRDFKPNLKV WFGATPVETT 600
  601 FRSEESLHCS IPPVSQVRNE QTHWMFTNRT TGDVEVPISL VRDDGVVYSS GLTFSYKSLE 660
  661 RHGPCRIVSN Y

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..191] MSA 1.022968 View MSA. No confident structure predictions are available.
    2 View Details [192..671] PSI-BLAST 1000.0 Crystal Structure of CSL bound to DNA


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.79

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle