Protein Overview: ncr-2

General Information:
Name(s) found:	ncr-2 / CE24891 [WormBase]
Description(s) found: Found 19 descriptions. SHOW ALL	WBGene00003562 locus:ncr-2 Niemann-Pick C1 protein homolog 2 status:Partially_confirmed UniProt:P34389 protein_id:CCD62644.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	1274 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA]
Biological Process:	cholesterol transport [IEA]
Molecular Function:	hedgehog receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRQGGGGGER MVSVLFLLLI HLALCQAKCV MTECDGEEDS NHPPCKTNKS TYLPITVTRS  60
   61 LNPTYMARFE KYCSYLVQEE DKAQVCCTEL QLKGMTDRIS NAATILGSCP SCFDNFAKLW 120
  121 CQFTCSPDQS KFMKVMETTG PKNVVVKMEF KVNRDFVEGL YESCRHTWFA NGLALRLMSL 180
  181 GGKVSFENFY GFMGTKNLAQ SIPINTEFQF SRMKNAMNIP TTPCHKSAGP KVPACGAIDC 240
  241 PTNAHQLVDI SKVEHLGTKV FHPHFPDFEW LLKICGCLAL TVLLVFILKY SCHRRSAPNG 300
  301 EDGCYVDLGK GNLEVQFEGL CARYANAVIK HPLIFVSLGL IVAAACCSGN FKFHSLTHSV 360
  361 DQVSAADGET RRNEKKFIHS FGPNHRIEQI FINLPPTTKS MFNMPLFEEM FQLVGNIQNL 420
  421 TACYGNSSVK LDDICYKPIG KNHGCAIMSP TNYFQNKWTN FENAGPPTID DEIFDDQHWE 480
  481 HLKYCIRNPL TVSTYSEMSC FGEFSGPIDP ILVFGGSNES IKGAEMYYTA RTIMITVLIR 540
  541 GPEDQAIAWE TAFLNMMSRY EMKHANFTFM TETSVAEEIH TAVETDKIVS VIACAAVLIW 600
  601 VITMLGINHW PESSILSALV HHKLLISISA VMISVISVWC SIGMFSLFGV HATDNAIVVL 660
  661 FFVITCLGIN RIFVIIRTFQ ANGHCYGLPN ISYREMNHRI SNVMRRSIPI VLTNSLICST 720
  721 CLFLAGGVLP YVSVSMPAVE VFARHAGLAI LMDTAFYLLV MLPLFQYDAR REMSGKCEIW 780
  781 PWYELSNESK INLCMEAVDG NLRSPVDWFK LAIAPLLLKK ICRIWIATFF FVSLIIACYC 840
  841 TLCLEFGFNQ VMAFSETSYL TKHFQNMNEN LNIGPPLWFV VEGDVKWHDP KMQNKFCTLA 900
  901 GCDDNSMGNK IRSLAYAENY KGNYLHGDVN IWLDSYLQFM HPRGSCCKMD GKQFCDPSNA 960
  961 THCSSCSSSS VASLTTTEYE FYRNLHHFLE TPPSIQCAHG GMALAKPAIN LTRNGKIQSA1020
 1021 YFSTFFKKLN LSDSIQLYDA WRFAKYLADD IERELEIPGV KVYVYSTFFP YYEQYLTLST1080
 1081 TVYTLVVLVL FVAFVTISLF LRVNLAGSLV TVFVLLSSYL HLMEWMYLLG ITVNVVSVIN1140
 1141 MAMSLGIAVE FFGQMLHGFY NSKKPKREER AFAALVSNGS TTLSGIFPAI MITAGCLSFA1200
 1201 DSRVLITYFC NQLVGIGLVC AVHGVVYMPT LLAIFGSDFY QNVSSEEEST DEAELQDTPP1260
 1261 STTSSTSSTS ETSV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-2	hcp2 ip from december	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ncr-2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: