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Protein Overview: deg-1

General Information:
Name(s) found: deg-1 / CE24854 [WormBase]
Description(s) found:
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  • WBGene00000950 locus:deg-1 Degenerin deg-1 status:Confirmed UniProt:P24585 protein_id:CCD67556.1 [WormBase]
  • gi|684988|gb|AAA99524.1| degenerin [Caenorhabditis elegans] [NCBI NR]
  • gi|20976713|gb|AAB07574.2| Degeneration of certain neurons protein 1 [Caenorhabditis elegans] [NCBI NR]
  • gi|17551326|ref|NP_509311.1| DEGeneration of certain neurons family member (deg-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|1706358|sp|P24585.2|DEG1_CAEEL RecName: Full=Degenerin deg-1; AltName: Full=Degeneration of certain neurons protein 1 [NCBI NR]
  • Degenerin deg-1 OS=Caenorhabditis elegans GN=deg-1 PE=1 SV=2 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE24854 WBGene00000950 locus:deg-1 status:Confirmed SW:P24585 protein_id:AAB07574.2 [wormpep150.fasta]
  • 24854 WBGene00000950 locus:deg-1 status:Confirmed SW:P24585 protein_id:AAB07574.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • DEGeneration of certain neurons DEG-1, putative ion channel (88.1 kD) (deg-1) [Caenorhabditis elegans]gi|20976713|gb|AAB07574.2| Degeneration of certain neurons protein 1 [Caenorhabditis elegans]gi|684988|gb|AAA99524.1| degeneringi|1706358|sp|P24585|DE [nrdb_11152004_Chlamydomonas]
  • locus:deg-1 status:Confirmed SW:P24585 protein_id:AAB07574.2 [wormpep115.fasta.reversed]
  • CE24854 locus:deg-1 status:Confirmed [wormpep80.hongbin]
  • CE24854 WBGene00000950 locus:deg-1 status:Confirmed UniProt:P24585 protein_id:AAB07574.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE24854 WBGene00000950 locus:deg-1 status:Confirmed UniProt:P24585 protein_id:AAB07574.2| [wormORF-contam.fasta]
  • DEGeneration of certain neurons family member (deg-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Degeneration of certain neurons protein 1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Degenerin deg-1 (Degeneration of certain neurons protein 1) [nr-271106-contam.fasta]
  • degenerin [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE24854 WBGene00000950 locus:deg-1 status:Confirmed UniProt:P24585 protein_id:CCD67556.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE24854 WBGene00000950 locus:deg-1 status:Confirmed UniProt:P24585 protein_id:CCD67556.1 Degenerin deg-1 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 778 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: sodium ion transport [IEALink to PubMed article]
    ion transport [IEALink to PubMed article]
    Molecular Function: ion channel activity [IEALink to PubMed article]
    sodium channel activity [IEALink to PubMed article]
    amiloride-sensitive sodium channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNHHSKTKK TSMLGREDYI YSHDITNKNK KEKLNGASKN NDYNQDDDDE TMKSKMMDFC  60
   61 DKTTAHGAKR VLIARNSFSK LMWGLIIFSF LLMFAYQASK LIFKFSAHEK ITDISLKFDD 120
  121 VEFPAITFCN LNPYKKSLVM MVPSIRDTMD VYDNAKTHSK SEGEKKKPKV SRKQHSDASQ 180
  181 QMVRELFAKE IEEGMVELKK SNKTLQSQNK SGRRRSQRSI ENRRYEAIEA HCKCVGNIGM 240
  241 ECIRFESPPR DPSSKCICTY DRDMEVAWPC FNISVWYDHE CPLCHDDGYC ESTLPSGTTS 300
  301 SDKWPCMCRN RGDTSERDDT PYCIGKAGVG KIEIRKLWLE NNMTTTSTTT TTTTTPPPTT 360
  361 TSTTTTTTTT PPPTTTARPN QRAIVSNPET IKAMGFQGMT DGVAMLTRAK ENLMFTMAAL 420
  421 SDKQRIALSQ SKHEFIEMCS FNGKECDIDE DFRLHVDPEF GNCFTFNYDV NNNYTSSRAG 480
  481 PMYGIRVLLF VNTSDYMSTS ESSGVRLAIH PPTEYPFPDT FGYSAPVGFA SSFGIKKKVM 540
  541 QRLPAPYGEC VETKKVVDRN YIYAGYDYHP EGCHRSCFQN GLIDDCSCGD PRFPVPEGYR 600
  601 HCSAFNATAR TCLEKNIGSV GDFHHITQKM DKCVCKQSCE EIIHEVTFSC SKWPSGATDL 660
  661 GDCDGMTESE CEQYYRLNAA MIEVFYEQLN YELLQESEAY GLVNLIADFG GHLGLWLGFS 720
  721 VITVMEVCVL LVDMISLFFK SRHEEKLLRQ STKRKDVPED KRQITVGSGR KSDAFVSI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..278] FFAS03 4.24 No description for 2qtsA was found.
    2 View Details [279..778] PSI-BLAST 91.0 No description for 2qtsA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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