Protein Overview: gap-2

General Information:
Name(s) found:	gap-2 / CE23476 [WormBase]
Description(s) found: Found 13 descriptions. SHOW ALL	WBGene00001516 locus:gap-2 status:Partially_confirmed UniProt:A6ZJ45 protein_id:CAO78710.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	790 amino acids
Gene Ontology:
Cellular Component:	intracellular [IEA]
Biological Process:	regulation of small GTPase mediated signal transduction [IEA] reproduction [IMP]
Molecular Function:	GTPase activator activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGEYDPWDP SFHNSSMIPY SLASIYPSIE NLPEEFSNEN NKIKNVLKNF IWSFKLKKNY  60
   61 VRVSSLFGEY CRYTVNTSHS DSGTSRIASA LGGKSSSQES PSLRIKARWQ SVHILPLRAY 120
  121 DNLLETLCYN YLPLCEQLEP VLNVRDKEDL ATSLVRVMYK HNLAKEFLCD LIMKEVEKLD 180
  181 NDHLMFRGNT LATKAMESFM KLVADDYLDS TLSDFIKTVL QCEDSCEVDP QKLGNVSNSS 240
  241 LEKNRALLMR YVEVAWTKIL NNVHQLPKNL RDVFSALRCR LEAQNREALA DTLISSSIFL 300
  301 RFLCPAILSP SLFNLVSEYP SPTNARNLTL IAKTLQNLAN FSKFGGKEPH MEFMNEFVDR 360
  361 EWHRMKDFLL RISSESKSGP EKNADAIVDA GKELSLIATY LEEAWTPLLQ EKNGNKHPLS 420
  421 NVKSVLSELA ECKRRSDNGV FHSPMVQQPS SDYENSPQQH VVPRHENVPA YRSTPPTGQA 480
  481 TVLGRSTNRP ATHLLTSDDY VLSSAFQTPS LRPGGTRLSD ETGTSSSRTS DKTTSSAEIR 540
  541 DDTDSDFELR EDRGRGGRNR KRLPRTDASP SSSQQASSGY LSNNPSRSSY SNSSSSSPVE 600
  601 RMAALSIANP VFGPGPSSGY AIPAEPKEIV YQKRASPPPY DPDVHNYHYQ PMQVYAVPPD 660
  661 CQVSPRTQAT GGVNAQNRLS LPRTNPRASR NSTLLRPSVV NVPDDWDRTS DYWRDRGENN 720
  721 YRSQLESQVE SQAREIERLM RENIELKSKM MSSTKTVDSK RSDSGASEDS YDSLSSLDRP 780
  781 SRQSLVVVPN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
binding	0.0816027554254649	bayes_pls_golite062009

Term	Confidence	Notes
enzyme regulator activity	0.68732227880003	bayes_pls_golite062009
nucleoside-triphosphatase regulator activity	0.590837939249671	bayes_pls_golite062009
GTPase regulator activity	0.59070509814251	bayes_pls_golite062009
enzyme activator activity	0.53004209819211	bayes_pls_golite062009
GTPase activator activity	0.528693496432149	bayes_pls_golite062009
small GTPase regulator activity	0.10243777232979	bayes_pls_golite062009
Ras GTPase activator activity	0.0454578418356197	bayes_pls_golite062009

No functions predicted.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.93

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..111]	PSI-BLAST	4.221849	Synaptogamin I
2	View Details	[112..475]	PSI-BLAST	74.0	RAS-GTPASE-ACTIVATING DOMAIN OF HUMAN P120GAP
3	View Details	[476..555]	deduced	N/A	No confident structure predictions are available.
4	View Details	[556..705]	MSA	7.228997	View MSA. No confident structure predictions are available.
5	View Details	[706..790]	deduced	N/A	No confident structure predictions are available.

Protein Overview: gap-2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: