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Protein Overview: frm-4

General Information:
Name(s) found: frm-4 / CE19698 [WormBase]
Description(s) found:
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  • WBGene00001491 locus:frm-4 status:Confirmed UniProt:H2KYZ6 protein_id:CCD65426.1 [WormBase]
  • gi|4887684|gb|AAD32269.1| Ferm domain (protein4.1-ezrin-radixin-moesin) family protein 4, isoform a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17505677|ref|NP_491586.1| FERM domain (protein4.1-ezrin-radixin-moesin) family member (frm-4) [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE19698 WBGene00001491 locus:frm-4 status:Confirmed TR:P91092 protein_id:AAD32269.1 [wormpep150.fasta]
  • 19698 WBGene00001491 locus:frm-4 status:Confirmed TR:P91092 protein_id:AAD32269.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • FERM domain (protein 4.1-ezrin-radixin-moesin) (71.8 kD) (frm-4) [Caenorhabditis elegans]gi|4887684|gb|AAD32269.1| Ferm domain (protein4.1-ezrin-radixin-moesin) family protein 4, isoform a [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:frm-4 status:Confirmed TR:P91092 protein_id:AAD32269.1 [wormpep115.fasta.reversed]
  • CE19698 locus:frm-4 status:Confirmed [wormpep80.hongbin]
  • CE19698 WBGene00001491 locus:frm-4 status:Confirmed UniProt:P91092_CAEEL protein_id:AAD32269.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE19698 WBGene00001491 locus:frm-4 status:Confirmed UniProt:P91092_CAEEL protein_id:AAD32269.1| [wormORF-contam.fasta]
  • Ferm domain (protein4.1-ezrin-radixin-moesin) family protein 4, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • FERM domain (protein4.1-ezrin-radixin-moesin) family member (frm-4) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE19698 WBGene00001491 locus:frm-4 status:Confirmed UniProt:P91092 protein_id:AAD32269.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE19698 WBGene00001491 locus:frm-4 status:Confirmed UniProt:H2KYZ6 protein_id:CCD65426.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Isoform of H2KYZ7, FERM domain (Protein4.1-ezrin-radixin-moesin) family OS=Caenorhabditis elegans GN=frm-4 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 635 amino acids

    Gene Ontology:
    Cellular Component: cytoskeleton [IEALink to PubMed article]
    Biological Process: protein amino acid dephosphorylation [IEALink to PubMed article]
    Molecular Function: protein tyrosine phosphatase activity [IEALink to PubMed article]
    cytoskeletal protein binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQNNTSSSF LGRLTTSTRS SFMSPKDVRC NVHLLHDSDI IGNEFPRTQS AQTILDYVCQ  60
   61 LKHIQEKDFL GLRYQDHHKH RYWLDLTRSI NHVVKNFKTE SMTLHLRFRY YPSDPARLRD 120
  121 PNLRYQLFVQ LQRDLLHGRL YCPTSSAAEL AALILQAQLG DYNEEKHVGN YVSGYKLLLK 180
  181 QTPKLEERIA NNHKELKGKS SESAELEFLE KASQLDTYAF DPYTIKEPHD TLPVYIGASC 240
  241 KGILIYTGQS RTHNIDWSEL VKVDYSGKEI RLTLSENYRG QITAAGTPTG TLNGHGPGSP 300
  301 SIMDKSLTKK PLTLKYTCPS GQFAKHLWIH ILSQQAFFNE TSAQDVKLKF SKPRIPLLSR 360
  361 GSTFRFPSKR VYREIEEEDS KSILFDKSIM ETSAVMNETT TSNENEESIL NCSTISAPLS 420
  421 SGSGVVRYDL LRQTPRVEQP WLKQNSLKVT TVHDNTASSS SSPDNSETQN NNLSKITNLN 480
  481 LSIEREVSTS PSTSPVPIVH TQQHSDHNSQ NLEKNGNGKL ANGGGSGVDL GKKTVHTNGT 540
  541 TLICTEEKQD SILSMDESLT SKSLISRIAN TCFVFFLILL LIVAIVIVLF EKSEDSAHND 600
  601 FIESHRALSD LRHLYYEPTR HYVVEQYRKH FGAKI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..361] PSI-BLAST 73.09691 No description for 2he7A was found.
    2 View Details [362..441] deduced N/A No confident structure predictions are available.
    3 View Details [442..635] MSA 1.204972 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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