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Protein Overview: eif-6

General Information:
Name(s) found: eif-6 / CE17565 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00001234 locus:eif-6 Eukaryotic translation initiation factor 6 status:Confirmed UniProt:O62106 protein_id:CAB16860.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 246 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    mature ribosome assembly [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: ribosome binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALRVDYEGS NDVGVFCTLT NSYCLVGVGG TQNFYSILEA ELSDLIPVVH TSIASTRIVG  60
   61 RLTVGNRHGL LVPNATTDQE LQHLRNSLPD EVAIRRVDER LSALGNVIAC NDHVAIVHAE 120
  121 ISAETEQALV EVLKVEVFRV SLAQNSLVGS YCILSSNGCL VAARTPPETQ REIAALLQIP 180
  181 VVAGTCNRGS ELIGAGMVVN DWVAFCGLDS TSTELSVVES IFKLGEQGAP TSISNQLRDT 240
  241 LIESML

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..246] PSI-BLAST 104.0 Ribosome anti-association factor eIF6 (aIF6)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation initiation factor activity
    		•  2.82313826209658 bayes_pls_golite062009
  • ribosomal large subunit binding
    		•  2.29551693750603 bayes_pls_golite062009
  • binding
    		•  1.48640777619976 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.14138534491569 bayes_pls_golite062009
  • hydrolase activity
    		•  1.05437300113124 bayes_pls_golite062009
  • catalytic activity
    		•  0.889920589881492 bayes_pls_golite062009
  • protein binding
    		•  0.21271994410782 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle