Protein Overview: unc-5

General Information:
Name(s) found:	unc-5 / CE16790 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00006745 locus:unc-5 Netrin receptor unc-5 status:Partially_confirmed UniProt:Q26261 protein_id:CCD61588.1 [WormBase] pir\|\|T32541 unc-5 protein - Caenorhabditis elegans [NCBI NR] gi\|54036553\|sp\|Q26261.2\|UNC5_CAEEL RecName: Full=Netrin receptor unc-5; AltName: Full=Uncoordinated protein 5; Flags: Precursor [NCBI NR] gi\|2662595\|gb\|AAB88355.1\| Uncoordinated protein 5, isoform a [Caenorhabditis elegans] [NCBI NR] gi\|17542652\|ref\|NP_500823.1\| UNCoordinated family member (unc-5) [Caenorhabditis elegans] [NCBI NR] Netrin receptor unc-5 OS=Caenorhabditis elegans GN=unc-5 PE=1 SV=2 [Swiss-Prot] [wormpep67.fasta] CE16790 WBGene00006745 locus:unc-5 axon guidance protein status:Partially_confirmed SW:Q26261 protein_id:AAB88355.1 [wormpep150.fasta] 16790 WBGene00006745 locus:unc-5 axon guidance protein status:Partially_confirmed TR:Q7KPX0 protein_id:AAB88355.1 [wormpep130-phg-ecoli-orf-rand.fasta] UNCoordinated locomotion UNC-5, unc-5 (101.6 kD) (unc-5) [Caenorhabditis elegans]gi\|2662595\|gb\|AAB88355.1\| Uncoordinated protein 5, isoform a [Caenorhabditis elegans]gi\|7511686\|pir\|\|T32541 unc-5 protein - Caenorhabditis elegansgi\|54036553\|sp\|Q26261\|UNC [nrdb_11152004_Chlamydomonas] CE16790 WBGene00006745 locus:unc-5 axon guidance protein status:Partially_confirmed TR:Q7KPX0 protein_id:AAB88355.1 [wormpep132.fasta] 16790 WBGene00006745 locus:unc-5 axon guidance protein status:Partially_confirmed SW:Q26261 protein_id:AAB88355.1 [wormpep150-phg-orf-ecoli-rand.fasta] locus:unc-5 axon guidance protein status:Partially_confirmed TR:O44171 protein_id:AAB88355.1 [wormpep115.fasta.reversed] CE16790 locus:unc-5 axon guidance protein status:Partially_confirmed [wormpep80.hongbin] CE16790 WBGene00006745 locus:unc-5 axon guidance protein status:Partially_confirmed UniProt:UNC5_CAEEL protein_id:AAB88355.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE16790 WBGene00006745 locus:unc-5 axon guidance protein status:Partially_confirmed UniProt:UNC5_CAEEL protein_id:AAB88355.1\| [wormORF-contam.fasta] Uncoordinated protein 5, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta] Netrin receptor unc-5 precursor (Uncoordinated protein 5) [nr-271106-contam.fasta] UNCoordinated family member (unc-5) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE16790 WBGene00006745 locus:unc-5 axon guidance protein status:Partially_confirmed UniProt:Q26261 protein_id:AAB88355.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE16790 WBGene00006745 locus:unc-5 axon guidance protein status:Partially_confirmed UniProt:Q26261 protein_id:CCD61588.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE16790 WBGene00006745 locus:unc-5 status:Partially_confirmed UniProt:Q26261 protein_id:CCD61588.1 Netrin receptor unc-5 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	919 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [RCA]
Biological Process:	motor axon guidance [IMP ] mesodermal cell migration [IMP] signal transduction [IEA] gonad morphogenesis [IMP ] positive regulation of axon extension [IMP] positive regulation of locomotion [IMP ]
Molecular Function:	protein binding [IEA] axon guidance receptor activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEITITTQP KSGYVIRNKP LRLQCRANHA TKIRYKCSSK WIDDSRIEKL IGTDSTSGVG  60
   61 YIDASVDISR IDVDTSGHVD AFQCQCYASG DDDQDVVASD VATVHLAYMR KHFLKSPVAQ 120
  121 RVQEGTTLQL PCQAPESDPK AELTWYKDGV VVQPDANVIR ASDGSLIMSA ARLSDSGNYT 180
  181 CEATNVANSR KTDPVEVQIY VDGGWSEWSP WIGTCHVDCP LLRQHAHRIR DPHDVLPHQR 240
  241 RTRTCNNPAP LNDGEYCKGE EEMTRSCKVP CKLDGGWSSW SDWSACSSSC HRYRTRACTV 300
  301 PPPMNGGQPC FGDDLMTQEC PAQLCTADSS RIVISDTAVY GSVASIFIVA SFILAILAMF 360
  361 CCKRGNSKKS KPLKPQKMNS EKAGGIYYSE PPGVRRLLLE HQHGTLLGEK ISSCSQYFEP 420
  421 PPLPHSTTLR SGKSAFSGYS STRNAGSRAA LIQECSSSSS GSGGKRTMLR TSSSNCSDDD 480
  481 NYATLYDYME DKSVLGLDTS QNIVAAQIDS NGARLSLSKS GARLIVPELA VEGEKMLYLA 540
  541 VSDTLTDQPH LKPIESALSP VIVIGQCDVS MSAHDNILRR PVVVSFRHCA STFPRDNWQF 600
  601 TLYADEGSGW QKAVTIGEEN LNTNMFVQFE QPGKKNDGFG WCHVMTYSLA RLMLAGHPRR 660
  661 NSLSAAKRVH LAVFGPTEMS AYRRPFELRV YCVPETGAAM ESVWKQEDGS RLLCESNDFI 720
  721 LNEKGNLCIC IEDVIPGFSC DGPEVVEISE TQHRFVAQNG LHCSLKFRPK EINGSQFSTR 780
  781 VIVYQKASST EPMVMEVSNE PELYDATSEE REKGSVCVEF RLPFGVKDEL ARLLDMPNES 840
  841 HSDWRGLAKK LHYDRYLQFF ASFPDCSPTS LLLDLWEASS SGSARAVPDL LQTLRVMGRP 900
  901 DAVMVLERFL SAFPQIVSP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: unc-5

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: