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Protein Overview: dnj-12

General Information:
Name(s) found: dnj-12 / CE16015 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00001030 locus:dnj-12 status:Confirmed UniProt:O45502 protein_id:CAB07390.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 402 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic cleavage [IMPLink to PubMed article]
    spindle organization [IMPLink to PubMed article]
    response to heat [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    protein folding [IEALink to PubMed article]
    Molecular Function: heat shock protein binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    unfolded protein binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKETGYYDV LGVKPDASDN ELKKAYRKMA LKFHPDKNPD GAEQFKQISQ AYEVLSDEKK  60
   61 RQIYDQGGEE ALQGGGGGGE GFHNPFDVFD MFFGGGGRGG RGERRVKPTV HNLRVTLDTL 120
  121 YKGVTKKLKI SRTATCKGCK GLGGNEGSAK ECSDCRGRGI KVRVIRMGPM VQQMQSHCDS 180
  181 CNGEGSTFLE KDRCKKCNGK KQVKEDEIIE VGITPGMKDG EKFVFEGKGD EVIGIEKPGD 240
  241 FVVVLDEVEH EKFVRKGDNL IIQHNIDLSE ALCGFVRTIS TLDGRTIFYR VLPGEVIAHA 300
  301 DVKVIHNEGM PMRRASSDKG DLLVQFDVKF PDKINPDAAK KLADLLPGKR EEIIDEDAEV 360
  361 VELTELDPQA SRRNFAERDD FEGHGGFGGH GHGPQGVQCQ QS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..93] PSI-BLAST 21.0 No description for 2ochA was found.
    2 View Details [94..402] PSI-BLAST 46.0 The crystal structure of Hsp40 Ydj1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.7298921704023 bayes_pls_golite062009
  • protein binding
    		•  2.6297172985864 bayes_pls_golite062009
  • protein disulfide isomerase activity
    		•  2.4409950647303 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing S-S bonds
    		•  2.4409950647303 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting keto- and enol-groups
    		•  2.23398279564144 bayes_pls_golite062009
  • unfolded protein binding
    		•  2.04158808514315 bayes_pls_golite062009
  • receptor binding
    		•  1.01508461105961 bayes_pls_golite062009
  • catalytic activity
    		•  0.276917867171685 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle