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Protein Overview: CE13473

General Information:
Name(s) found: CE13473 [WormBase]
Description(s) found:
Found 23 descriptions.
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  • WBGene00020383 Probable mitochondrial import inner membrane translocase subunit tim-44 status:Confirmed UniProt:O02161 protein_id:CCD71993.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 425 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial inner membrane presequence translocase complex [IEALink to PubMed article]
    Biological Process: nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    intracellular protein transport [IEALink to PubMed article]
    reproduction [IMPLink to PubMed articleLink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: P-P-bond-hydrolysis-driven protein transmembrane transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRICGNGI RLTRTRLQFQ PSIVTFRDYS NPAPKRGFLN NLIDNVRDEM QKNKELQEHQ  60
   61 QQLKARMQEL NESDALKDAR KKFEIVEKET LKSSEVVKQK IEELSDHMKK MVHEIQKTEA 120
  121 GKKMTEAGAE ALKQARKAAE HVEKVAEKVG DTEVYKHVST SMKTVKDEID NIADVRMYSR 180
  181 PEALTKRTDG FDLEKERVVE ANDSATDVTL HKDSKWYSGW KNFSESNTYY HKLLDWKIKY 240
  241 DESDNMAVRM MRGVTEKIGS VFSGQNEVSE VLTEIHKIDA NFDKQEWLRF CETKIIPNIL 300
  301 EAFIRFDLEV LQSWCHERAY TQLSTVVKEY QKMHFSTKDS RIIDINKVEM ATGKMMEQGP 360
  361 VLIISFQVYM INVTKNADGK VVEGDPDNPK RINHIWVLCR DVEEYNPALA WKLLEVHMQE 420
  421 TPLAL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..240] FFAS03 1.09 Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
    2 View Details [241..425] PSI-BLAST 55.30103 Crystal structure of human Tim44 C-terminal domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle