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Protein Overview: fib-1

General Information:
Name(s) found: fib-1 / CE12920 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00001423 locus:fib-1 rRNA 2'-O-methyltransferase fibrillarin status:Confirmed UniProt:Q22053 protein_id:CAB01657.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 352 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    nucleolus [IDALink to PubMed article]
    Biological Process: nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    rRNA processing [IEALink to PubMed article]
    positive regulation of embryonic development [IMPLink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    reproduction [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: RNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRPEFNRGG GGGGFRGGRG GDRGGSRGGF GGGGRGGYGG GDRGSFGGGD RGGFRGGRGG  60
   61 GDRGGFRGGR GGGDRGGFGG RGSPRGGFGG RGSPRGGRGS PRGGRGGAGG MRGGKTVVVE 120
  121 PHRLGGVFIV KGKEDALATK NMVVGESVYG EKRVSVDDGA GSIEYRVWNP FRSKLAASIM 180
  181 GGLENTHIKP GTKLLYLGAA SGTTVSHCSD VVGPEGIVYA VEFSHRSGRD LLGVAKKRPN 240
  241 VVPIVEDARH PHKYRMLVGM VDVIFSDVAQ PDQARIVALN AQNFLRNGGH AVISIKANCI 300
  301 DSTAEPEAVF AGEVNKLKEE KFKPLEQVTL EPYERDHAVV VAVYRPVKGK KV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..122] FFAS03 2.37 Crystal structure of the C-terminal domain of BclA, the major antigen of the exosporium of the Bacillus anthracis spore.
    2 View Details [123..352] PSI-BLAST 119.0 No description for 2ipxA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle