YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: gas-1

General Information:
Name(s) found: gas-1 / CE11980 [WormBase]
Description(s) found:
SHOW ONLY BEST
  • WBGene00001520 locus:gas-1 Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial status:Confirmed UniProt:Q93873 protein_id:CAB01886.1 [WormBase]
  • pir||T23532 hypothetical protein K09A9.5 - Caenorhabditis elegans [NCBI NR]
  • gi|3878424|emb|CAB01886.1| C. elegans protein K09A9.5, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|3183092|sp|Q93873.2|NDUS2_CAEEL RecName: Full=Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; AltName: Full=NADH-ubiquinone oxidoreductase 49 kDa subunit; AltName: Full=Complex I-49kD; Short=CI-49kD; Flags: Precursor [NCBI NR]
  • gi|17568379|ref|NP_510569.1| General Anaesthetic Sensitivity abnormal family member (gas-1) [Caenorhabditis elegans] [NCBI NR]
  • (Q93873) Probable NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-49KD) (CI-49KD) [Swiss-Prot]
  • Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Caenorhabditis elegans GN=gas-1 PE=3 SV=2 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE11980 WBGene00001520 locus:gas-1 NADH-ubiquinone oxidoreductase 49KD subunit status:Confirmed SW:Q93873 protein_id:CAB01886.1 [wormpep150.fasta]
  • 11980 WBGene00001520 locus:gas-1 NADH-ubiquinone oxidoreductase 49KD subunit status:Confirmed SW:Q93873 protein_id:CAB01886.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • nadh dehydrogenase, General Anaesthetic Sensitivity abnormal GAS-1 (54.6 kD) (gas-1) [Caenorhabditis elegans]gi|3878424|emb|CAB01886.1| Hypothetical protein K09A9.5 [Caenorhabditis elegans]gi|7505618|pir||T23532 hypothetical protein K09A9.5 - Caenorhabd [nrdb_11152004_Chlamydomonas]
  • locus:gas-1 NADH-ubiquinone oxidoreductase 49KD subunit status:Confirmed SW:Q93873 protein_id:CAB01886.1 [wormpep115.fasta.reversed]
  • CE11980 locus:gas-1 NADH-ubiquinone oxidoreductase 49KD subunit status:Confirmed SW:Q93873 protein_id:CAB01886.1 [wormpep80.hongbin]
  • CE11980 WBGene00001520 locus:gas-1 NADH-ubiquinone oxidoreductase 49KD subunit status:Confirmed UniProt:Q93873 protein_id:CAB01886.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE11980 WBGene00001520 locus:gas-1 NADH-ubiquinone oxidoreductase 49KD subunit status:Confirmed UniProt:Q93873 protein_id:CAB01886.1| [wormORF-contam.fasta]
  • Hypothetical protein K09A9.5 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • General Anaesthetic Sensitivity abnormal family member (gas-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial precursor (NADH-ubiquinone oxidoreductase 49 kDa subunit) (Complex I-49kD) (CI-49kD) [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE11980 WBGene00001520 locus:gas-1 status:Confirmed UniProt:Q93873 protein_id:CAB01886.1 Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 482 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: electron transport [IEALink to PubMed article]
    mitochondrial electron transport, NADH to ubiquinone [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    response to drug [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: NADH dehydrogenase (quinone) activity [IEALink to PubMed article]
    NAD or NADH binding [IEALink to PubMed article]
    metal cluster binding [IEALink to PubMed article]
    electron carrier activity [IEALink to PubMed article]
    oxidoreductase activity, acting on NADH or NADPH [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGRKIAGTC LRANVPSVAA TSSTPATQTR NSHTIWYPDA KFERQFKTGG TLGKLWMSER  60
   61 VSDFDEKIGL DKLEKLAYSD PVMSDNYSGK QREKNLENMI LNFGPQHPAA HGVLRLVLKL 120
  121 EGEVIIKAIP HIGLLHRATE KLIEHKTYTQ ALPYFDRLDY VSMMCNEQAW SLAVEKLLGI 180
  181 DIPTRAKYIR TLMGELTRIQ NHIMGITTHA LDVGAMTPFF WMFEEREKLF EFSERVSGAR 240
  241 MHANYVRPGG VAWDLPIGLM DDIYDWAIKF PERIDELEDM LTENRIWKAR TIDIGLVSAA 300
  301 DALNWGFSGV MVRGSGIKQD VRKTEPYDAY ADMEFDVPIG TKGDCYDRYL CRIEEMRQSL 360
  361 NIVHQCLNKM PAGEIKVDDH KVVPPKRAEM KENMESLIHH FKFFTEGFQV PPGATYVPIE 420
  421 APKGEFGVYL VADGTGKPYR CFIRAPGFAH LAAIHDVCYM SLIADIVAVI GTMDIVFGEV 480
  481 DR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..82] PSI-BLAST 12.39794 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
    2 View Details [83..482] PSI-BLAST 120.0 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • NADH dehydrogenase activity
    		•  13.5914597754866 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  12.311192040385 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  12.1563727867842 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  11.7527486559512 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  11.1653559876285 bayes_pls_golite062009
  • oxidoreductase activity
    		•  6.49653654839585 bayes_pls_golite062009
  • ferredoxin hydrogenase activity
    		•  3.63852106070173 bayes_pls_golite062009
  • oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
    		•  3.63852106070173 bayes_pls_golite062009
  • oxidoreductase activity, acting on hydrogen as donor
    		•  3.45611813853803 bayes_pls_golite062009
  • oxidoreduction-driven active transmembrane transporter activity
    		•  2.72460560332491 bayes_pls_golite062009
  • oxidoreductase activity, acting on iron-sulfur proteins as donors
    		•  2.45015987642707 bayes_pls_golite062009
  • electron carrier activity
    		•  1.58392879810571 bayes_pls_golite062009
  • catalytic activity
    		•  1.13542026154948 bayes_pls_golite062009
  • binding
    		•  0.855276486319983 bayes_pls_golite062009
  • protein binding
    		•  0.33547765747527 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle