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Protein Overview: nhx-6

General Information:
Name(s) found: nhx-6 / CE11382 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00003734 locus:nhx-6 Sodium\/hydrogen exchanger status:Confirmed UniProt:H2L039 protein_id:CCD71272.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 634 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: sodium ion transport [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    regulation of pH [IEALink to PubMed article]
    Molecular Function: solute:hydrogen antiporter activity [IEALink to PubMed article]
    sodium:hydrogen antiporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLIRRLSVV LIGLLLILGY AQAECDEKEE EVFPSRYPIA YFKWEEVKIP MTICLWLIAA  60
   61 SISKIVFNSI PHLNDLFPDS ALLIMIGLII GIIFKLIGVD KNQFFLESEI FMLYLLPPLV 120
  121 FDAGYFMPAR QFFDNFGSIM CFAMIGTLFN FLAISFSLWA ISLTGLFSVE TPLLHMLLFG 180
  181 SVAADVDPVA VIVIFEELAV NDVLFIAVFG ESLFNDGVSV VLYRMFLTFS EIGAENLIPE 240
  241 DFANGGVSFL VVVFGGVGIG VLFAFLASLL TKYSRAEEIS ILNCVFILIL PYTCYLCGEL 300
  301 FGLSSIIAVV FCGALMRQYC RENVEQETVK ATEKFIKVLS IASETVIFVF LGLSTVSSNH 360
  361 HWDTCFIVLT VVFCLIYRTL GVVVMCHFLN KYRLNKYTKV DQFIMAYGGL RGAIAYGLVV 420
  421 AIPDFIPAKN MFVTSCIIVI YFTVFLQGIT LKPIAEFLQV EKKNVHSKNM IEHIYTELID 480
  481 TTMAGMEDIA GFKGHHWIRD SWNYFNNCYL RPVLVNKNNM KQMDKTKLVR KYKHLVDEDA 540
  541 KKIANGGDLK SNLAFTRALI EHTRSRTNTA ITSDSNGKID FVTHMKEHHG ITVYDHENNV 600
  601 EYTSDYMENE SEDGEYKNGG FESDGSSDNF EERV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..106] deduced N/A No confident structure predictions are available.
    2 View Details [107..465] FFAS03 1.08 Crystal structure of the Na+/H+ antiporter NhaA
    3 View Details [466..634] FFAS03 1.49 human APP core domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  1.38049042607606 bayes_pls_golite062009
  • protein binding
    		•  0.910693622624617 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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