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Protein Overview: CE09078

General Information:
Name(s) found: CE09078 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00008411 locus:mans-1 status:Confirmed UniProt:P90787 protein_id:CAA98114.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 540 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: determination of adult lifespan [IMP]
    Molecular Function: calcium ion binding [IEALink to PubMed article]
    mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLRSHEQLV VCVGVMFLLT VCITAFFFLP SGGADLYFRE ENSVHVRDVL IREEIRRKEQ  60
   61 DELRRKAEEA NPIPIPKPEI GASDDAEGRR IFVKQMIKFA WDGYRKYAWG ENELRPNSRS 120
  121 GHSSSIFGYG KTGATIIDAI DTLYLVGLKE EYKEARDWIA DFDFKTSAKG DLSVFETNIR 180
  181 FTGGLLSAFA LTGDKMFLKK AEDVATILLP AFETPSGIPN SLIDAQTGRS KTYSWASGKA 240
  241 ILSEYGSIQL EFDYLSNLTG NPVFAQKADK IRDVLTAMEK PEGLYPIYIT MDNPPRWGQH 300
  301 LFSMGAMADS WYEYLLKQWI ATGKKDDRTK REYEEAIFAM EKRMLFKSEQ SNLWYFAKMN 360
  361 GNRMEHSFEH LACFSGGMVV LHAMNEKNKT ISDHYMTLGK EIGHTCHESY ARSTTGIGPE 420
  421 SFQFTSSVEA KTERRQDSYY ILRPEVVETW FYLWRATKDE KYRQWAWDHV QNLEEYCKGT 480
  481 AGYSGIRNVY ESSPEQDDVQ QSFLFAELFK YLYLIFSEDN ILPLDQWVFN TEAHPFRIRH 540
  541

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..540] PSI-BLAST 177.0 Structure of mouse Golgi alpha-1,2-mannosidase IA reveals the molecular basis for substrate specificity among Class I enzymes (family 47 glycosidases)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • mannosyl-oligosaccharide mannosidase activity
    		•  7.089685350864 bayes_pls_golite062009
  • mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
    		•  6.95179264736435 bayes_pls_golite062009
  • mannosidase activity
    		•  5.20286438265852 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  4.31319275372149 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  3.65589746311782 bayes_pls_golite062009
  • hydrolase activity
    		•  2.67964748309919 bayes_pls_golite062009
  • binding
    		•  1.49199031708525 bayes_pls_golite062009
  • catalytic activity
    		•  1.31873306707813 bayes_pls_golite062009
  • cation binding
    		•  0.362242764130218 bayes_pls_golite062009
  • metal ion binding
    		•  0.362242764130218 bayes_pls_golite062009
  • protein binding
    		•  0.36081692928767 bayes_pls_golite062009
  • ion binding
    		•  0.355220167272296 bayes_pls_golite062009
  • calcium ion binding
    		•  0.121126738064555 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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