Protein Overview: CE08947

General Information:
Name(s) found:	CE08947 [WormBase]
Description(s) found: Found 21 descriptions. SHOW ALL	WBGene00008258 locus:mans-2 Mannosyl-oligosaccharide 1,2-alpha-mannosidase C52E4.5 status:Confirmed UniProt:Q18788 protein_id:CAB01415.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	590 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA]
Biological Process:	nematode larval development [IMP]
Molecular Function:	calcium ion binding [IEA] mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTVRFNKQA LAILAACFIF LLCVVCYFSA SSESHNAVVV GERARGHIAV RDVENRHLAE  60
   61 EKHAVIHAKT VGKIERVVSQ EKVEILRPAR VESKPPGEKT STEPEETGVG KAPIQTSEGL 120
  121 EKLIGKIHYE NKDEENDLRR QKVKEMMIHA WEGYKNYSWG ANELRPMSKK PNSQNIFGGS 180
  181 QMPATIVDAA DTLFIMDLKD KYKEARDYIE NNFSMAKSTS TLSVFETTIR FLGGLLSLYA 240
  241 LTQESFYIEK AREVGEALLP AFNTPSGIPK SNLDVASKHA SNYGWANGGQ SILSEIGSLH 300
  301 LEFLYLSRIS NAPIFEKKVK KVRDALEKAE KPNGLYSNYI NPDTGKFTGS HMSLGALGDS 360
  361 FYEYLIKSYV QSNYTDTQAK NMYWDVSDAI QKHMIKVSKQ SNLTYTVELN NGQAQHKMGH 420
  421 LACFVPGMFA LQAINEDTEE EKLRIMTLAE ELAKTCHESY IRSETHIGPE MFYFNERDEA 480
  481 TSKHSENGYI QRPEVIEGWF YLWRLTGKTM YRDWVWDAVQ AIEKYCRVDS GFTGLQNVYN 540
  541 PKAGREDVMQ SFFLAEFLKY AYLTFADESL ISLDKWVFNT EAHPVPVLTN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
mannosyl-oligosaccharide mannosidase activity	7.089685350864	bayes_pls_golite062009
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	6.95179264736435	bayes_pls_golite062009
mannosidase activity	5.20286438265852	bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds	4.31319275372149	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	3.65589746311782	bayes_pls_golite062009
hydrolase activity	2.67964748309919	bayes_pls_golite062009
binding	1.49199031708525	bayes_pls_golite062009
catalytic activity	1.31873306707813	bayes_pls_golite062009
cation binding	0.362242764130218	bayes_pls_golite062009
metal ion binding	0.362242764130218	bayes_pls_golite062009
protein binding	0.36081692928767	bayes_pls_golite062009
ion binding	0.355220167272296	bayes_pls_golite062009
calcium ion binding	0.121126738064555	bayes_pls_golite062009

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..121]	deduced	N/A	No confident structure predictions are available.
2	View Details	[122..590]	PSI-BLAST	1000.0	Structure of mouse Golgi alpha-1,2-mannosidase IA reveals the molecular basis for substrate specificity among Class I enzymes (family 47 glycosidases)

Protein Overview: CE08947

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: