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Protein Overview: sams-1

General Information:
Name(s) found: sams-1 / CE08852 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00008205 locus:sams-1 Probable S-adenosylmethionine synthase 1 status:Confirmed UniProt:O17680 protein_id:CAB03975.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 403 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: negative regulation of multicellular organism growth [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    one-carbon metabolic process [IEALink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    methionine adenosyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKFLFTSE SVSEGHPDKM CDQISDAVLD AHLKQDPNAK VACETVTKTG MVMLCGEITS  60
   61 KAVVDYQVLV RRVIEKIGFT DSSIGFDHKT CNVLVALEQQ SPEIAAGVHV NKDGEDVGAG 120
  121 DQGIMFGYAT DETEETMPLT LILSHKINAE LHKLRRNGTL PWVRPDSKSQ VTIEYESRHG 180
  181 ATIPLRVHTV VVSTQHSPDV TLEKLRETIL ADVIKKVIPA SLLDESTVFH INPCGTFIVG 240
  241 GPMGDAGVTG RKIIVDTYGG WGAHGGGAFS GKDPTKVDRS AAYAARWVAT SLVKAGLAKR 300
  301 VLVQLSYAIG IAKPISVLVY AFGTSPLTDE ELHQIVEDSF DLTPGKIIKE LDLKRPIYEK 360
  361 TAENGHFGHS EFPWEQPKAL KISPALLEKA KGNPIPATSA IAH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..403] PSI-BLAST 1000.0 Methionine Adenosyltransferase complexed with a L-methionine analogous

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • methionine adenosyltransferase activity
    		•  8.00759843092519 bayes_pls_golite062009
  • transferase activity
    		•  1.78879119839291 bayes_pls_golite062009
  • binding
    		•  1.70779292877479 bayes_pls_golite062009
  • catalytic activity
    		•  1.59111295908728 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  1.11999094477144 bayes_pls_golite062009
  • protein binding
    		•  0.298204436433395 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle