Protein Overview: unc-41

General Information:
Name(s) found:	unc-41 / CE08425 [WormBase]
Description(s) found: Found 19 descriptions. SHOW ALL	WBGene00006777 locus:unc-41 Adaptor complexes medium subunit family status:Partially_confirmed UniProt:P90761 protein_id:CAB02795.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	1657 amino acids
Gene Ontology:
Cellular Component:	clathrin adaptor complex [IEA] synapse [IDA]
Biological Process:	vesicle-mediated transport [IEA] embryonic development ending in birth or egg hatching [IMP] intracellular protein transport [IEA] protein secretion [IMP] positive regulation of locomotion [IMP]
Molecular Function:	protein binding [IEA][IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSFTQSIED EGPPELPASL DIDMIEGVSM KTSDTNDTII EVKPGKVDPQ LGETQKYKMA  60
   61 VPGPGHSEQE QELHKSLIRD EEEDAEVEQV FAASAEPVVT PPKSLNFAET AEELRHAYDQ 120
  121 KIRKRPTTPT SACVLDGIAF FAGSVDGSND TIPTDAEKKI KVSIPSGRRR KTENMSYSEF 180
  181 YESMANQIPG GGGRRMSQSG RTTPLHDYEG DILDENPQYK DKAPPAPVVH RRSSIEWENF 240
  241 ADMEDKMEQA EEKARKEEKK EKEETAEVAQ NDDVTTEKHQ NEVEKSKKML NFLAKPPTVE 300
  301 ITSPDAPHQG AFHDNTPKEP KVVEEEEDDD LPTFSEDMDE ARQQVMKEMT ESVVKTENVE 360
  361 NEKQEDTHIS EGHVEYGTEE SPAVTDGSYQ QDGTENAYDP NAYPGYIWNY ETQEWEYDPS 420
  421 YVAPEEPIDQ SAYEAQAAAY AEVDQRAAEV VYQREHAGYD QGDFYTHQDT SYSSEAYAHD 480
  481 QAKGYQDPNA YGAEAAADNS QEYDYSAYGG YEGYLAACRA YDEESQQPQY GETVATEAYS 540
  541 QDYGYEQQGD YHHEGVGATD ENSTSAISGY EQNGASTSLG YGDAQGYDGY DHNASYYQGQ 600
  601 EYQQEYYQNH KYENSQYQVD QHPAESAAPP RPVAPMEPLF KQAPPQPDPF GWDSSGHTGD 660
  661 APTASEPVQE LSPTPEASSS TGTSAPARPP PARPEAPKKD ETAVDAAAPP RPPPAARPPP 720
  721 PRPAPANKEK PKEPEPEEDA WAQFKRMTEK VSTAVKSTES TLKNLEETSA ANDIKDESYL 780
  781 ANVGGSQGFV NESTQKEIQR LTEEKKMEKL QKKKLKQQGK KAATPTLEPD EEDAMDRAAQ 840
  841 ELAMKMASMR SDMADWKAPE MIPVKEIKKA PEIRRVDSAS AIPPRKRSSI KDVQQDSGGS 900
  901 LELPPHLAAP QDSIAPNPKG DHAPDDPILS APAWADFETS EPMLPPSESG FFSNKDASNE 960
  961 GGVSRDATDD PFVTTVASSE KRSSFVADPF APQQAALIDE SYDPFAVVAV EEVVAMAKAK1020
 1021 AEQAAANAEN EDDFYNGRQS PTLSTPTPEG GSPISQQRPN AFEDDFKCAE LTGLDTPTPL1080
 1081 YDEDDSQPLT DFIPKFDGDG WDLMVRHPIK KKSFMAERCW KPCYVRLHGL TLYLYNDKKD1140
 1141 AQPIQELLLQ ATYSLSDTTL QAYDVYGKIH TVKLQFVVYK EKVGIRPGQI SRLVDGHITK1200
 1201 YGLPLEHSAQ CTVLLKFGSL NASHLQTFVT TVEDLLFKCK ITRTAKPVYK QDEVQIHCYD1260
 1261 EYSAFVDKEG ILSDQKARVR LFCLAFLTGS PVLEVGLNDR RRQGKEIVRR KDILPMYTER1320
 1321 WIRFEALEFH SIVNKPEFDK EQVIAFSPPD GCFFEIMRFR VRPPRNREKA MTVKSIMKIA1380
 1381 GSKVEIRIEA MAAAQIQRTR GSDERRNIPC EDIAIRFPIP EAWIYLFREE RHWGVGSIHS1440
 1441 KKLRPGKVKN LKDRLLGAVQ ASEPNLIECA IGEAKYEHVY RSLVWRIPRL PEKHHAAYKS1500
 1501 HLLKCRFELS SFDLMPEEFL PRCDVDFTMP LATVSNTVVR SVSVEQHEDS DRVEKFVRYV1560
 1561 AKYQYKVEID YVQCADLDLD MADPSVNPEA AAAPVPELHQ PTFNPSTQES DTQQGYRIDF1620
 1621 NEAEMGGSNR RDDSSSDEEP DSHKMPIIQI DMKNYGY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-1	hcp1 IP from december2004	Cheeseman, I.M., et al. (2005)
View Run	hcp-2	hcp2 ip from december	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: unc-41

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: