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Protein Overview: mec-8

General Information:
Name(s) found: mec-8 / CE08260 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00003172 locus:mec-8 status:Confirmed UniProt:G5ECJ4 protein_id:CAB03111.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 312 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: mechanosensory behavior [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    response to mechanical stimulus [IMPLink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGPKPNLAS AASMESLNSV SSEATNPSQV RTLFVSGLPM DAKPRELYLL FRGCRGYEGA  60
   61 LLKMTSKNGK PTSPVGFVTF LSQQDAQDAR KMLQGVRFDP ECAQVLRLEL AKSNTKVARP 120
  121 KQSPPPPQHA ALSAAAAGVP QFLAPMQHDL LLDPQSAALF NEQQLLALSL PHLHAAQALQ 180
  181 AAYMPASALQ QYSQNQLFAA AQMHPAAAAA ASLQHSQQAS QASTSACSTL FVANLSAEVN 240
  241 EDTLRGVFKA FSGFTRLRLH NKNGSCVAFV EYSDLQKATQ AMISLQGFQI TANDRGGLRI 300
  301 EYARNKMADV NG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..312] PSI-BLAST 21.0 No description for 2ghpA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.86761524461453 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.727288287394927 bayes_pls_golite062009
  • protein binding
    		•  0.426607329742248 bayes_pls_golite062009
  • RNA binding
    		•  0.299180957062386 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.73

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle