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Protein Overview: CE06555

General Information:
Name(s) found: CE06555 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00012302 locus:dot-1.3 status:Partially_confirmed UniProt:Q23200 protein_id:CAA93538.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 365 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: histone-lysine N-methyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDANNTEHFY HHRSRNNQQS VLTKNNHVNH LRQIPNLCSL EITMPVIHLS SARKGNAEFK  60
   61 FPNTLHFRQT VKEMFEEIYK PILDAVKVPL PSDAVVGNPD KFSQYIDALN LKLAHPDVLS 120
  121 RVPAKHHEIT STRLCSLTVA IKLAELAYRF SVPDANVLRH YAVGTSTVYG ELHCSQMASF 180
  181 VDQLNMGPSD YFMDLGSGIG HLVNFVAAYA RTQMSVGVEL MDNLAEIAEK NKEFNERLLN 240
  241 HFGKKVYATR FIHGSFTSPA VIREIQTKAT VILANNVRFD PELKLQLKEI LMGCKDRTRI 300
  301 ISSEPLVPSR ARQTNSRRAD DFVKISDESL LNLVDNNVSW TSRKVPFYLT TINRNKVSFF 360
  361 YCVRF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..365] PSI-BLAST 58.154902 Catalytic, N-terminal domain of histone methyltransferase Dot1l

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.723277178398499 bayes_pls_golite062009
  • transferase activity
    		•  0.64512166557639 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.54403439349476 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.54389223881989 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle