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Protein Overview: gstk-2

General Information:
Name(s) found: gstk-2 / CE04296 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00017054 locus:gstk-2 Glutathione s-transferase kappa 2 status:Confirmed UniProt:Q18973 protein_id:CCD63360.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 225 amino acids

    Gene Ontology:
    Cellular Component: outer membrane-bounded periplasmic space [IEALink to PubMed article]
    Biological Process: NONE FOUND
    Molecular Function: protein disulfide oxidoreductase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNRKVVKFF FDVISPYSYF GFEGITRHRS VWKTPIQMKP FFFAGVVRHT ENPGLPLRIP  60
   61 IKEKYMHKDL LFSAQYWGIP FRLPKDYTNM MLNTSSIVPQ RILVASQLRD NVLMEDVARG 120
  121 LWHRFYAYGK PIFTKSQVAE VLRDLHVKDV DELVMMSDSA EVKNILRENT DEAIGNGCFG 180
  181 APWMHITDGH GKVLQTVFGS DRLPQVADFL AEPFKGPMRE KKPNA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..225] PSI-BLAST 44.69897 Crystal structure of Mitochondrial class kappa glutathione transferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glutathione transferase activity
    		•  3.10261229787796 bayes_pls_golite062009
  • antioxidant activity
    		•  2.98988279939823 bayes_pls_golite062009
  • glutathione binding
    		•  2.53131331487579 bayes_pls_golite062009
  • glutathione peroxidase activity
    		•  2.45655797002775 bayes_pls_golite062009
  • peroxidase activity
    		•  2.09720157676308 bayes_pls_golite062009
  • oxidoreductase activity, acting on peroxide as acceptor
    		•  2.09720157676308 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.66622364190158 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  1.44229450804826 bayes_pls_golite062009
  • disulfide oxidoreductase activity
    		•  0.713619215118063 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  0.15984522114548 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle