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Protein Overview: unc-115

General Information:
Name(s) found: unc-115 / CE02176 [WormBase]
Description(s) found:
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  • WBGene00006839 locus:unc-115 status:Confirmed UniProt:Q95QM5 protein_id:CAC70079.1 [WormBase]
  • gi|71987001|ref|NP_001024542.1| UNCoordinated family member (unc-115) [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_509702.2| UNCoordinated locomotion UNC-115, putative actin-binding protein family member (72.2 kD) (unc-115) [Caenorhabditis elegans] [NCBI NR]
  • gi|15718124|emb|CAC70079.1| C. elegans protein F09B9.2b, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE02176 WBGene00006839 locus:unc-115 LIM domains status:Confirmed TR:Q95QM5 protein_id:CAC70079.1 [wormpep150.fasta]
  • 02176 WBGene00006839 locus:unc-115 LIM domains status:Confirmed TR:Q95QM5 protein_id:CAC70079.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • UNCoordinated locomotion UNC-115, putative actin-binding protein family member (72.2 kD) (unc-115) [Caenorhabditis elegans]gi|15718124|emb|CAC70079.1| Hypothetical protein F09B9.2b [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:unc-115 LIM domains status:Confirmed TR:Q95QM5 protein_id:CAC70079.1 [wormpep115.fasta.reversed]
  • CE02176 LIM domains status:Confirmed TR:Q95QM5 protein_id:CAC70079.1 [wormpep80.hongbin]
  • CE02176 WBGene00006839 locus:unc-115 LIM domains status:Confirmed UniProt:Q95QM5_CAEEL protein_id:CAC70079.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE02176 WBGene00006839 locus:unc-115 LIM domains status:Confirmed UniProt:Q95QM5_CAEEL protein_id:CAC70079.1| [wormORF-contam.fasta]
  • Hypothetical protein F09B9.2b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • UNCoordinated family member (unc-115) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE02176 WBGene00006839 locus:unc-115 LIM domains status:Confirmed UniProt:Q95QM5 protein_id:CAC70079.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE02176 WBGene00006839 locus:unc-115 status:Confirmed UniProt:Q95QM5 protein_id:CAC70079.1 [wormpep246-ecoli-contam.fasta]
  • Uncharacterized protein OS=Caenorhabditis elegans GN=unc-115 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 639 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: negative regulation of multicellular organism growth [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    cytoskeleton organization [IEALink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    Molecular Function: actin filament binding [IDALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    actin binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFSRPVLSV NHLILGKKCD VCRKKCSGDV LKANDKYFHI NCFQCKKCGR NLGETGFYTT  60
   61 PENAYLCPDD FRAVSKEITV KTTTQQAHAS SSSAATPKSP EKSNGTTDVS SSGAANATLQ 120
  121 QISPLGSPTT CAACDQALHS GQVLLALGLS WHVYCFKCSE CSAVLHGEYM SHHGKPLCLR 180
  181 DYNEKFGVKC YECEKFIAGK VLQAGGYKFH PTCARCSRCG SHFGDGEEMY MQGDEIWHPS 240
  241 CEHARTTENI APTGRAATLS RNEPKYQSTF GQHQAYMYLL PEVEQTYLRH PVMNAKEPNA 300
  301 PQYHVPQGPI KIRKSRMSML KTGMQRLTED LEKNIPRPKS PHMDNEEPIE LAHYPAAHVP 360
  361 DPDTLPAIER EDFPAPQFPY AVEELKRRLS TSSVENEISD DEYSESDKVD EDKLRKTVET 420
  421 LEKYNDSSIA HVIRQNIEDS HKKQRLPLHW DPRNASRTPS GKKMPHLKFR YDVPINASPS 480
  481 RHLNRPRPWV VWQGGERDQG NNTLPCFHIP EDSRANTLRA ATLPTEFGQN LSLENLDTTI 540
  541 SSHYSEHSTT ESGTAGGPRS AGGAVLRSSL PDMSKPAKQY DLLFLQTTNS DLPEDVDRQH 600
  601 LERHLPRDQF EEIFKMSLIE FYKLPEWKRI NLKRKHKLF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..194] PSI-BLAST 46.154902 No description for 2i13A was found.
    2 View Details [195..443] FFAS03 2.38 No description for 2dfyX was found.
    3 View Details [444..576] deduced N/A No confident structure predictions are available.
    4 View Details [577..639] PSI-BLAST 29.045757 Solution structure of the Villin headpiece domain of human actin-binding LIM protein homologue (KIAA0843 protein)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  0.890394134199723 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle