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Protein Overview: nduf-2.2

General Information:
Name(s) found: nduf-2.2 / CE00702 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00006463 locus:nduf-2.2 status:Partially_confirmed UniProt:Q22800 protein_id:CCD63209.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 474 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: electron transport [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: NADH dehydrogenase (quinone) activity [IEALink to PubMed article]
    NAD or NADH binding [IEALink to PubMed article]
    metal cluster binding [IEALink to PubMed article]
    electron carrier activity [IEALink to PubMed article]
    oxidoreductase activity, acting on NADH or NADPH [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRSLHPLR AVACARPAIS NRDSHTIWYP DAKFERQFKT GGTLGKLWMS ERVSDFDDQI  60
   61 GLDKLEKLAY SDPVLSDNYE GKKREKNLEN MILNFGPQHP AAHGVLRLVL KLEGEVIIKA 120
  121 IPHIGLLHRA TEKLIEHKTY TQALPYFDRL DYVSMMCNEQ AFSLAIEKLL GIDVPPRAKY 180
  181 IRILFGELTR IQNHIMGITT HALDVGAMTP FFWMFEEREK LFEFSERVSG ARMHANYVRP 240
  241 GGVAWDLPVG LMDDIYDWAV KFPARIDELE DMLTENRIWK ARTVDIGLVS ASDALNWGFS 300
  301 GVMVRGSGIK QDVRKTEPYD AYADMEFDVP IGTKGDCYDR YLCRVEEMRQ SLNIVHQCLN 360
  361 KMPTGEIKSD DHKVVPPKRA EMKENMESLI HHFKFFTEGF QVPPGATYVP IEAPKGEFGV 420
  421 YLVADGTGKP YRCFIRAPGF AHLAAIHDVC YMSLIADIVA VIGTMDIVFG EVDR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..73] PSI-BLAST 15.30103 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
    2 View Details [74..474] PSI-BLAST 122.0 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • NADH dehydrogenase activity
    		•  13.5914597754866 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  12.311192040385 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  12.1563727867842 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  11.7527486559512 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  11.1653559876285 bayes_pls_golite062009
  • oxidoreductase activity
    		•  6.49653654839585 bayes_pls_golite062009
  • ferredoxin hydrogenase activity
    		•  3.63852106070173 bayes_pls_golite062009
  • oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
    		•  3.63852106070173 bayes_pls_golite062009
  • oxidoreductase activity, acting on hydrogen as donor
    		•  3.45611813853803 bayes_pls_golite062009
  • oxidoreduction-driven active transmembrane transporter activity
    		•  2.72460560332491 bayes_pls_golite062009
  • oxidoreductase activity, acting on iron-sulfur proteins as donors
    		•  2.45015987642707 bayes_pls_golite062009
  • electron carrier activity
    		•  1.58392879810571 bayes_pls_golite062009
  • catalytic activity
    		•  1.13542026154948 bayes_pls_golite062009
  • binding
    		•  0.855276486319983 bayes_pls_golite062009
  • protein binding
    		•  0.33547765747527 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.54

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle