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Protein Overview: SPAC824.07

General Information:
Name(s) found: SPAC824.07 [Sanger Pombe]
Description(s) found:
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  • pir||T39108 probable hydroxyacylglutathione hydrolase - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74638888|sp|Q9UT36.1|GLO21_SCHPO RecName: Full=Probable hydroxyacylglutathione hydrolase C824.07; AltName: Full=Glyoxalase II; Short=Glx II [NCBI NR]
  • gi|6013104|emb|CAB57337.1| hydroxyacylglutathione hydrolase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19114358|ref|NP_593446.1| hydroxyacylglutathione hydrolase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • hydroxyacylglutathione hydrolase [Sanger Pombe]
  • Probable hydroxyacylglutathione hydrolase C824.07 OS=Schizosaccharomyces pombe GN=SPAC824.07 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE HYDROXYACYLGLUTATHIONE HYDROLASE: Q9UT36; [pompepVF.fasta]
  • PUTATIVE HYDROXYACYLGLUTATHIONE HYDROLASE.: Q9UT36; [pompepV13]
  • Putative hydroxyacylglutathione hydrolase [pompep4896]
  • |||putative hydroxyacylglutathione hydrolase [pompepnew.fasta]
  • SPAC824.07 protein [4896.FASTAC]
  • |||hydroxyacylglutathione hydrolase (predicted)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • putative hydroxyacylglutathione hydrolase. [Schizosaccharomyces pombe]gi|6013104|emb|CAB57337.1| SPAC824.07 [Schizosaccharomyces pombe]gi|7492662|pir||T39108 probable hydroxyacylglutathione hydrolase - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||hydroxyacylglutathione hydrolase |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (Q9UT36) Putative hydroxyacylglutathione hydrolase [pompep4896_normal_reversed]
  • SPAC824.07 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC824.07 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Probable hydroxyacylglutathione hydrolase C824.07 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC824.07 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 256 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: sulfur metabolic process [RCALink to PubMed article]
    response to methylglyoxal [NASLink to PubMed article]
    methylglyoxal catabolic process to D-lactate [ISSLink to PubMed article]
    cellular response to stress [IEPLink to PubMed article]
    Molecular Function: hydroxyacylglutathione hydrolase activity [ISSLink to PubMed article]
    zinc ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFHITPIWM WKGTGNNYAY LLTCDKTKIT AIVDPAEPES VIPVIKEKTA KKEIDLQYIL  60
   61 TTHHHYDHAG GNEDILSYFP SLKVYGGKNA SGVTYTPKDK EIFKVGEVQV EALHTPCHTQ 120
  121 DSICYYVSSP SKRAVFTGDT LFTSGCGRFF EGDAKQMDYA LNHVLAALPD DTVTYPGHEY 180
  181 TKSNAKFSST IFSTPELTKL VDFCKNHEST TGHFTIGDEK KFNPFMCLGL ESVQKAVGSS 240
  241 DPITVMKKLR DMKNAA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..256] PSI-BLAST 51.39794 Glyoxalase II (hydroxyacylglutathione hydrolase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydroxyacylglutathione hydrolase activity
    		•  3.53012507604564 bayes_pls_golite062009
  • catalytic activity
    		•  0.941400907161877 bayes_pls_golite062009
  • binding
    		•  0.900972948435178 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  0.802604883362264 bayes_pls_golite062009
  • hydrolase activity
    		•  0.021392930321391 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle