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Protein Overview: urg1

General Information:
Name(s) found: urg1 / SPAC1002.19 [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • GTP cyclohydrolase II [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 439 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: riboflavin biosynthetic process [IEA]
    Molecular Function: GTP binding [IEA]
    GTP cyclohydrolase II activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLATEQSRPA ECNGAHAHEK TEEVKKPLYS RPVVLTTYPS QSRIDPFPMN WGAATAEERG  60
   61 PITVARSIET LPHRNAVGAH GGSYSVYNAL AVAGGFLPPD HRPNFELTEP TFDFPELDSW 120
  121 HDPKKIVAMD PYGHLTPSVF KKYLDEGYDV RPTIAITRAH LQVTEIQRSV ENGSLPIDGK 180
  181 IVLNEKGDIA VTKVAVEPVW YLPGVAERFG VDEVTLRRAL FEQMGGAYPE LITRPDIKVF 240
  241 LPPIGGLTAY IFGPPEYLSD TSKSLAVRVH DECNGSDVFQ SDICTCRPYL TFGIEEAAKE 300
  301 AQNGGAGLVV YFRKEGRALG EVVKYLVYNK RKRTGDSAEN YFKRTEELAG VRDMRFQALM 360
  361 PDILHWFGIK KIDRMLSMSN MKHDAIVGQG IKILNRITIP DDLIPEDSQV EIDAKIQSGY 420
  421 FSEKKVTEDD LSCVHGRHW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..211] PSI-BLAST 55.522879 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
    2 View Details [212..439] PSI-BLAST 70.30103 Crystal Structure of E. coli GTP cyclohydrolase II in complex with GTP analogue, GMPcPP, and Zinc

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.265221777506021 bayes_pls_golite062009
    2
    Term Confidence Notes
  • catalytic activity
    		•  0.641212200472049 bayes_pls_golite062009
  • binding
    		•  0.541272319408336 bayes_pls_golite062009
  • hydrolase activity
    		•  0.282917045029035 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle