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Protein Overview: srb8

General Information:
Name(s) found: srb8 / SPAC688.08 [Sanger Pombe]
Description(s) found:
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  • gi|7768483|emb|CAB90774.1| mediator complex subunit Srb8 (PMID 12738880) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|46397047|sp|Q9P6L8.1|SRB8_SCHPO RecName: Full=Mediator of RNA polymerase II transcription subunit 12; AltName: Full=Mediator complex subunit 12; AltName: Full=Suppressor of RNA polymerase B srb8 [NCBI NR]
  • gi|19114978|ref|NP_594066.1| mediator complex subunit Srb8 [Schizosaccharomyces pombe] [NCBI NR]
  • mediator complex subunit Srb8 [Sanger Pombe]
  • Mediator of RNA polymerase II transcription subunit 12 OS=Schizosaccharomyces pombe GN=srb8 PE=1 SV=1 [Swiss-Prot]
  • PUTATIVE RNA POLYMERASE II HOLOENZYME AND KORNBERG'S MEDIATOR (SRB) SUBCOMPLEX SUBUNIT; SIMILAR TO S. CEREVISIAE SRB8: Q9P6L8; [pompepVF.fasta]
  • PUTATIVE SUBUNIT OF RNA POLYMERASE II HOLOENZYME AND KORNBERG'S MEDIATOR (SRB) SUBCOMPLEX; BY SIMILARITY TO YEAST SRB8: Q9P6L8; [pompepV13]
  • Similar to a region of yeast SRB8, a component of RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex [pompep4896]
  • |||putative RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit [pompepnew.fasta]
  • Suppressor of RNA polymerase B srb8 [4896.FASTAC]
  • |srb8||RNA polymerase II holoenzyme component (PMID 12738880)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • similar to a region of yeast SRB8, a component of RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex [Schizosaccharomyces pombe]gi|7768483|emb|CAB90774.1| SPAC688.08 [Schizosaccharomyces pombe]gi|46397047|sp|Q9P6L8|SRB8_SCHPO Suppress [nrdb_11152004_Chlamydomonas]
  • |srb8||mediator complex submodule |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (Q9P6L8) Similar to a region of yeast SRB8, a component of RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex [pompep4896_normal_reversed]
  • hypothetical protein SPAC688.08 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPAC688.08 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
    • Organism: Schizosaccharomyces pombe
    Length: 1233 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNRDSANPP GFNDAVPLAI CYIDSSTSSH DEYLTLLQSK VSAPDKNFRD ETVDGAPFLA  60
   61 GDAISKGHRY SPPVRSDRAS AQGLLQQHLE KSSTLENLKR YSSTLLGRQN DAVIDEPFAP 120
  121 FRPPPRVTLS ESRRDRWLQG LSDPMVPLSS LIKTIPHGLW GEDILRMLVK FRVPFTRAIW 180
  181 FIRCAGVNEA RSFLRKVQTT DITEWVKNWT DVAAGFLISF ISSFLNADIY SFADDYTYLL 240
  241 KLFGRLLAEE LVSPKHFLLR IVSFSGDSSL KSFSLHFFAL QFFSTSLIQY THICRKCVIT 300
  301 ILQSYQQLIV DQPANLLKFS LLSKKVSHFL FTLAQKNIES FFFPTEWDKL KPTIILLWKD 360
  361 FPNYSTLLSI MQERNSKAMY MYKPVTSSIR FLQIISCLSF PVGWRTLAKD LFKLLPVYTG 420
  421 VPLLLHWCIN CRSIFSGDRN FIVSSIFDNA NFDRNLIVDL TLSFVLKLHP LEYNECVAAA 480
  481 QLLDHLAACG YFFFSKYIAR LASLGYLRES MLNSSFMDDQ RKILVQLPIL RMSQQLKNKI 540
  541 YYILSKGNYF VDWSICDEYV KRFKEDHFSF MFKKEENYAI ITLSLVKIAS TPMSKLYEDY 600
  601 LVMLFAFHYS MFQVMTKLIA DNLVHFSFQS CACQTLFFIC SVVPKTESQK LLLNEMGKLF 660
  661 QVELNFSYDS PDVNLLIEQF YEITSYESNY DDAFVEYKDA TVANRKDFIE FLFHNITVSS 720
  721 KHTAVIFTSD LLMVLKIALN HPPYFDDLAT TTFSSLLKRD ECTILSFFKI LQFYGCKLLS 780
  781 VDQIWAVVSD VYEAQDNNTT LKQFFNYLLD ESTWPEGYLE ERHWRSILCK EARKHDSGLK 840
  841 LFKLGIKLCT RNEQIMKTIW SFIHVHDCNV ISEVIPDQRF LRTLTEHFMI DLRQLDIVTC 900
  901 LKKALVTLDE FSAPLYATWL TTLDDDELSE LTDDVVQKKV LESLDNYKSG IWKLVLSGLP 960
  961 NCKTVFEHLL LFSLEERLDL PAAFLQDLIG ASAYVMEQVP DSWFLEKLPC PLTQSLQSFS1020
 1021 HLSNHIEVLD STRQSRLTFL CHLILHMHGF VELTDQLATL ESLTIRKCIY RNQELLDLLL1080
 1081 FSIHLVKPNV ETNDEVCNTL KAWENIESRP YTIDFPEALQ QYSPRIVLHL FSFFYWKCQH1140
 1141 DDYLQENTSS KNNLLQKEWI LITKKKVILE QCEYVILDIL NFLKFSGIPT QSKKRLEVHM1200
 1201 LNFISSTLYL KVSFCSSNFL FKTISVLVYD LIT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..118] deduced N/A No confident structure predictions are available.
    2 View Details [119..222] Pfam 36.508638 No description for PF09497.1 was found. No confident structure predictions are available.
    3 View Details [223..342] MSA 1.04298 View MSA. No confident structure predictions are available.
    4 View Details [343..552] deduced N/A No confident structure predictions are available.
    5 View Details [553..689] deduced N/A Confident ab initio structure predictions are available.
    6 View Details [690..813] deduced N/A Confident ab initio structure predictions are available.
    7 View Details [814..959] deduced N/A No confident structure predictions are available.
    8 View Details [960..1233] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.79

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle