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Protein Overview: ure2

General Information:
Name(s) found: ure2 / SPAC1952.11c [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
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  • urease [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 835 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    Biological Process: urea metabolic process [IEA]
    nitrogen compound metabolic process [IEA]
    Molecular Function: nickel ion binding [IEA]
    urease activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQPRELHKLT LHQLGSLAQK RLCRGVKLNK LEATSLIASQ IQEYVRDGNH SVADLMSLGK  60
   61 DMLGKRHVQP NVVHLLHEIM IEATFPDGTY LITIHDPICT TDGNLEHALY GSFLPTPSQE 120
  121 LFPLEEEKLY APENSPGFVE VLEGEIELLP NLPRTPIEVR NMGDRPIQVG SHYHFIETNE 180
  181 KLCFDRSKAY GKRLDIPSGT AIRFEPGVMK IVNLIPIGGA KLIQGGNSLS KGVFDDSRTR 240
  241 EIVDNLMKQG FMHQPESPLN MPLQSARPFV VPRKLYAVMY GPTTNDKIRL GDTNLIVRVE 300
  301 KDFTEYGNES VFGGGKVIRD GTGQSSSKSM DECLDTVITN AVIIDHTGIY KADIGIKNGY 360
  361 IVGIGKAGNP DTMDNIGENM VIGSSTDVIS AENKIVTYGG MDSHVHFICP QQIEEALASG 420
  421 ITTMYGGGTG PSTGTNATTC TPNKDLIRSM LRSTDSYPMN IGLTGKGNDS GSSSLKEQIE 480
  481 AGCSGLKLHE DWGSTPAAID SCLSVCDEYD VQCLIHTDTL NESSFVEGTF KAFKNRTIHT 540
  541 YHVEGAGGGH APDIISLVQN PNILPSSTNP TRPFTTNTLD EELDMLMVCH HLSRNVPEDV 600
  601 AFAESRIRAE TIAAEDILQD LGAISMISSD SQAMGRCGEV ISRTWKTAHK NKLQRGALPE 660
  661 DEGSGVDNFR VKRYVSKYTI NPAITHGISH IVGSVEIGKF ADLVLWDFAD FGARPSMVLK 720
  721 GGMIALASMG DPNGSIPTVS PLMSWQMFGA HDPERSIAFV SKASITSGVI ESYGLHKRVE 780
  781 AVKSTRNIGK KDMVYNSYMP KMTVDPEAYT VTADGKVMEC EPVDKLPLSQ SYFIF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..258] PSI-BLAST 104.0 Urease, beta-subunit; Urease, gamma-subunit
    2 View Details [259..835] PSI-BLAST 177.0 alpha-Subunit of urease; alpha-subunit of urease, catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nickel ion binding
    		•  1.80580363718742 bayes_pls_golite062009
  • catalytic activity
    		•  0.907182340515553 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle