Protein Overview: top2

General Information:
Name(s) found:	top2 / SPBC1A4.03c [Sanger Pombe]
Description(s) found: Found 17 descriptions. SHOW ALL	DNA topoisomerase II [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	1485 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] nuclear chromosome [NAS]
Biological Process:	mRNA export from nucleus [IMP] mitotic chromosome condensation [IMP] transcription of nuclear rRNA large RNA polymerase I transcript [IGI] resolution of meiotic recombination intermediates [IMP] DNA topological change [IDA][IGI][IMP] chromatin organization [IGI]
Molecular Function:	ATP binding [IC] DNA topoisomerase (ATP-hydrolyzing) activity [IDA][IGI][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIDADFSDY EDEASGDENV LPNTTTKRKA STTSSKSRAK KASTPDLRQT SLTSMTASEQ  60
   61 IPLVTNNGNG NSNVSTQYQR LTPREHVLRR PDTYIGSIEP TTSEMWVFDS EKNKLDYKAV 120
  121 TYVPGLYKIF DEIIVNAADN KVRDPNMNTL KVTLDPEANV ISIYNNGKGI PIEIHDKEKI 180
  181 YIPELIFGNL LTSSNYDDNQ KKVTGGRNGY GAKLCNIFST EFVVETADKE RMKKYKQTWY 240
  241 DNMSRKSEPV ITSLKKPDEY TKITFKPDLA KFGMDKIDDD MVSIIKRRIY DMAGTVRETK 300
  301 VYLNNERISI SGFKKYVEMY LASDTKPDEE PPRVIYEHVN DRWDVAFAVS DGQFKQVSFV 360
  361 NNISTIRGGT HVNYVANKIV DAIDEVVKKE NKKAPVKAFQ IKNYVQVFVN CQIENPSFDS 420
  421 QTKETLTTKV SAFGSQCTLS DKFLKAIKKS SVVEEVLKFA TAKADQQLSK GDGGLRSRIT 480
  481 GLTKLEDANK AGTKESHKCV LILTEGDSAK SLAVSGLSVV GRDYYGVFPL RGKLLNVREA 540
  541 SHSQILNNKE IQAIKKIMGF THKKTYTDVK GLRYGHLMIM TDQDHDGSHI KGLIINYLES 600
  601 SYPSLLQIPG FLIQFITPII KCTRGNQVQA FYTLPEYEYW KEANNNGRGW KIKYYKGLGT 660
  661 SDHDDMKSYF SDLDRHMKYF HAMQEKDAEL IEMAFAKKKA DVRKEWLRTY RPGIYMDYTQ 720
  721 PQIPIDDFIN RELIQFSMAD NIRSIPSVVD GLKPGQRKVV YYCFKRNLVH ETKVSRLAGY 780
  781 VASETAYHHG EVSMEQTIVN LAQNFVGSNN INLLMPNGQF GTRSEGGKNA SASRYLNTAL 840
  841 SPLARVLFNS NDDQLLNYQN DEGQWIEPEY YVPILPMVLV NGAEGIGTGW STFIPNYNPK 900
  901 DITANLRHML NGEPLEIMTP WYRGFRGSIT KVAPDRYKIS GIINQIGENK VEITELPIRF 960
  961 WTQDMKEYLE AGLVGTEKIR KFIVDYESHH GEGNVHFNVT LTEAGMKEAL NESLEVKFKL1020
 1021 SRTQATSNMI AFDASGRIKK YDSVEDILTE FYEVRLRTYQ RRKEHMVNEL EKRFDRFSNQ1080
 1081 ARFIHMIIEG ELVVSKKKKK DLIVELKEKK FQPISKPKKG HLVDLEVENA LAEEEQSGDV1140
 1141 SQDEDSDAYN YLLSMPLWSL TYERYVELLK KKDEVMAELD ALIKKTPKEL WLHDLDAFEH1200
 1201 AWNKVMDDIQ REMLEEEQSS RDFVNRTKKK PRGKSTGTRK PRAIAGSSSS TAVKKEASSE1260
 1261 SKPSTTNRKQ QTLLEFAASK EPEKSSDINI VKTEDNSHGL SVEENRISKS PGLDSSDSGK1320
 1321 SRKRSQSVDS EDAGSKKPVK KIAASASGRG RKTNKPVATT IFSSDDEDDL LPSSLKPSTI1380
 1381 TSTKASAKNK GKKASSVKKQ SPEDDDDDFI IPGSSSTPKA SSTNAEPPED SDSPIRKRPT1440
 1441 RRAAATVKTP IYVDPSFDSM DEPSMQDDSF IVDNDEDVDD YDESD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: top2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: