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Protein Overview: SPCC1739.06c

General Information:
Name(s) found: SPCC1739.06c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • uroporphyrin methyltransferase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 496 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: methionine biosynthetic process [ISSLink to PubMed article]
    sulfur metabolic process [ISSLink to PubMed article]
    heme biosynthetic process [ISSLink to PubMed article]
    siroheme biosynthetic process [IEA]
    Molecular Function: uroporphyrin-III C-methyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIVSWSLKDA VVVVVGSGKN AYRRVNLCLS ENSSKIFWFC RSSADGGFDV GHLQLDAKKS  60
   61 DAIEILPISE FDPVRSLTTL GKEETDFLVD AVFVSESNHH EKEILHRTCK RYRIPLNIID 120
  121 NPSLCSFTLP ATWSEPPLQI SLSTSSNGCR LAQRLLRHVV SSLPSGMPEA IERFGRVRAI 180
  181 TKTPEKKQWI NHVSDFWPLE KLVRMTEDDL LAIVSDNFSL PLSSSQSSSL ANSYESLSTT 240
  241 LDKPSLTLDP EAFPTHKRGS IALIGSGPGS PDLLTVAARK AIMKADYVLA DKLVPEAVLQ 300
  301 LIPRHTPLFI ARKFPGNADK AQDELHQVAF DALSRGDYVV RLKQGDPYIY GRGGEEYLFF 360
  361 TQHGYVPTVI PGISSALMAP ISAGIPVTHR GVADQFLVCT GTGQKGSMPK IPSFVPTQTT 420
  421 VFLMALHRLE ILVQALIESG WPRVLPVCIA ERVSCPDQRF IFSTLEDVVE EYNKYESLPP 480
  481 GLLITGYSCN TLRNTA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..496] PSI-BLAST 109.0 Structure and function of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • uroporphyrin-III C-methyltransferase activity
    		•  3.573271502205 bayes_pls_golite062009
  • C-methyltransferase activity
    		•  3.35393353163232 bayes_pls_golite062009
  • precorrin-2 dehydrogenase activity
    		•  2.63318043162058 bayes_pls_golite062009
  • precorrin-4 C11-methyltransferase activity
    		•  2.18371138649366 bayes_pls_golite062009
  • catalytic activity
    		•  1.48349578618275 bayes_pls_golite062009
  • transferase activity
    		•  0.912524944496351 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.463693177369635 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.454156823400351 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  0.418775403210681 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  0.323461631906645 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.32207755075663 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle