Protein Overview: nuc1

General Information:
Name(s) found:	nuc1 / SPBC4C3.05c [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	pir\|\|JS0080 DNA-directed RNA polymerase (EC 2.7.7.6) I 189K chain - fission yeast (Schizosaccharomyces pombe) [NCBI NR] gi\|3334489\|sp\|P15398.2\|RPA1_SCHPO RecName: Full=DNA-directed RNA polymerase I subunit rpa1; AltName: Full=DNA-directed RNA polymerase I 190 kDa polypeptide; AltName: Full=DNA-directed RNA polymerase I largest subunit [NCBI NR] gi\|2832886\|emb\|CAA16827.1\| DNA-directed RNA polymerase I complex large subunit Nuc1 [Schizosaccharomyces pombe] [NCBI NR] gi\|19113092\|ref\|NP_596300.1\| DNA-directed RNA polymerase I complex large subunit Nuc1 [Schizosaccharomyces pombe] [NCBI NR] gi\|173433\|gb\|AAA35326.1\| RNA polymerase I largest subunit [Schizosaccharomyces pombe] [NCBI NR] DNA-directed RNA polymerase I complex large subunit Nuc1 [Sanger Pombe] DNA-directed RNA polymerase I subunit rpa1 OS=Schizosaccharomyces pombe GN=rpa1 PE=1 SV=2 [Swiss-Prot] DNA-DIRECTED RNA POLYMERASE I 190 KD SUBUNIT: P15398; [pompepVF.fasta] DNA-DIRECTED RNA POLYMERASE I 190 KD POLYPEPTIDE: P15398; [pompepV13] DNA-directed RNA polymerase I 190 kDa polypeptide (EC 2.7.7.6) [pompep4896] \|nuc1\|rpa1\|DNA-directed RNA polymerase I large subunit (PMID 2537310) [pompepnew.fasta] \|nuc1\|rpa1\|localization DNA-directed RNA polymerase I complex (large subunit) (PMID 2537310)\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pombe041504.fasta] \|nuc1\|rpa1\|localization DNA-directed RNA polymerase I complex \|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pompep2242005.fasta] dna-directed rna polymerase i 190 kd polypeptide [Schizosaccharomyces pombe]gi\|2832886\|emb\|CAA16827.1\| nuc1 [Schizosaccharomyces pombe]gi\|3334489\|sp\|P15398\|RPA1_SCHPO DNA-directed RNA polymerase I 190 kDa polypeptidegi\|82799\|pir\|\|JS0080 DNA-directed RN [nrdb_11152004_Chlamydomonas] (P15398) DNA-directed RNA polymerase I 190 kDa polypeptide (EC 2.7.7.6) [pompep4896_normal_reversed] \|nuc1\|rpa1\|DNA-directed RNA polymerase I complex large subunit Nuc1\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta] DNA-directed RNA polymerase I 190 kDa polypeptide [nr-271106-contam.fasta] RNA polymerase I largest subunit [nr-271106-contam.fasta] hypothetical protein SPBC4C3.05c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] SPBC4C3.05c [Schizosaccharomyces pombe] [nr-271106-contam.fasta] DNA-directed RNA polymerase I subunit rpa1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rpa1 PE=1 SV=2 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	1689 amino acids
Gene Ontology:
Cellular Component:	DNA-directed RNA polymerase I complex [ISS] cytosol [IDA]
Biological Process:	mRNA export from nucleus [IMP] nucleolus organization [IMP] transcription from RNA polymerase I promoter [ISS] protein localization to nucleolar rDNA repeats [IMP]
Molecular Function:	magnesium ion binding [IEA] DNA binding [IEA] zinc ion binding [IEA] DNA-directed RNA polymerase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIAQPVSSE IKSVKFGIYD VDDVEKISVK QIVNPVLLDN LNHPTNGGLY DLALGPYLKN  60
   61 SVCATCHLDE RYCPGHFGHI VLPIPAYHPL FFSQMYNLLR STCLYCHHFK LSKVKVHLFF 120
  121 CRLKLLDYGL LNESEMVENV SLTEAIIKNS NGTPLEDGSD SEDSGLGHDD IAKDAATLMR 180
  181 IRDEFVAKSI ADSRQNAHID AQLTTLLLHE RKKVVRAFYH AISSRKQCDN CQSFSPNFRK 240
  241 EGFAKIFEIP LSGKNLQFME QTGKIRSDVL RDTSKKHHED EGYDGDSDSS NESEVEGIDL 300
  301 FEEDPNPLKN KSKSPIAHGA KYMTSTEVRN HLRRLFVKEN VVLSRLYAHK RGKPASADMF 360
  361 FLQNIAVPPT RFRPASKMGD EVHENIQNEL LTRILQSSIQ IASLSKDSTV EVNPDEKEGL 420
  421 ERRSRAFELL INAFVQLQHD VNSLIDSNRN PSSGGQSRTV PPGIKQILEK KEGLFRKHMM 480
  481 GKRVNYAARS VISPDPNIET NEIGVPPVFA TKLTYPEPVT LYNFNEMRNA VINGPHKWPG 540
  541 ASHIQNEDGT LISLMPLTIE QRTALANQLL TPQSNLISSP YSYSRLINTN KKVYRHVRNG 600
  601 DMLILNRQPT LHKPSMMAHK ARILPGEKTI RMHYANCNSY NADFDGDEMN MHFPQSTNAR 660
  661 SEAQFIANTD SQYLVPTSGD PLRGLIQDHV VMGVWLTCKD TFYTRDEYQQ LLFQALKPDE 720
  721 TGMYGRIKTL PPAIQRPGIY WTGKQIISSV LLNLKPSDRP GLNLKSKAKV PGKYWSPDSE 780
  781 EGSVLFDDGE LLCGILDKSS FGASAFGLVH SVHELYGPDI AGRLLSVLSR LFTAYAQMRG 840
  841 FTCRMDDLRL DEQGDNWRRQ LLENGKSFGL EAASEYVGLS TDSPIALLNA NLEEVYRDDE 900
  901 KLQGLDAAMK GKMNGLTSSI INKCIPDGLL TKFPYNHMQT MTVSGAKGSN VNVSQISCLL 960
  961 GQQELEGRRV PLMVSGKSLP SFVPYETSAK SGGFIASRFL TGIAPQEYYF HCMAGREGLI1020
 1021 DTAVKTSRSG YLQRCLMKHL EGLCVQYDHT VRDSDGSIVQ FHYGEDSLDV TKQKHLTQFE1080
 1081 FSAKNYKSLI QKYKVKSVLS AVDSETASSY AKKALKKPYK YDPVLDKYPP SRYLGSVSEK1140
 1141 FQRAVDEYTQ KNPDKLIASK KESKLDDSLL NESKFKALMQ LRYQQSLVDP GESVGVLASQ1200
 1201 SIGEPSTQMT LNTFHFAGFG AKNVTLGIPR LREIIMTASA NIQTPTMTLR LNDGVSDKRA1260
 1261 SAFCKEVNKL VLSEVVRQVR VTEKISGQGS DEQSKTYAIR LDLYSRDEYQ DEYGVLQEEI1320
 1321 ESTFSNRFLK ILNRIIKSYL AKSKQRKSGG KDDTVPEVGQ ALKPLEDIDE APIEGRAQEA1380
 1381 LEDEDNDATN EKMVSRSKQH ASYEGPDEAD KVALRQLKGS NKVEDVNMDE EEDEGFKSDE1440
 1441 SVSDFKERKL LEKQNTVSIS ERRELQLKTA KEILSNCKHL DFDYVNGEWA TVELVFPINT1500
 1501 EKLLMVSLVE KACSETVIHE IPGITRCFSK PPDSALDTVP KVITEGVNLK AIWEFYNEIS1560
 1561 MNDIYTNDIA AILRIYGVEA ARNAIVHEVS SVFGVYGIAV DPRHLSLIAD YMTFEGGYKA1620
 1621 FNRMGIEYNT SPFAKMSFET TCHFLTEAAL RGDVDDLSNP SSRLVVGRVG NFGTGSFDIF1680
 1681 TPVVDSPAN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: nuc1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: