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Protein Overview: dna2

General Information:
Name(s) found: dna2 / SPBC16D10.04c [Sanger Pombe]
Description(s) found:
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  • pir||T39568 hypothetical helicase - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|4481950|emb|CAB38508.1| DNA replication endonuclease-helicase Dna2 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19113291|ref|NP_596499.1| DNA replication helicase Dna2 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|15213981|sp|Q9URU2.1|DNA2_SCHPO RecName: Full=DNA replication ATP-dependent helicase dna2 [NCBI NR]
  • DNA replication endonuclease-helicase Dna2 [Sanger Pombe]
  • DNA replication ATP-dependent helicase dna2 OS=Schizosaccharomyces pombe GN=dna2 PE=1 SV=1 [Swiss-Prot]
  • DNA REPLICATION AND REPAIR HELICASE; OKAZAKI FRAGMENT PROCESSING: O74241;Q9URU2;Q9UUK8; [pompepVF.fasta]
  • DNA replication helicase dna2 [pompep4896]
  • |dna2||DNA replication helicase [pompepnew.fasta]
  • |dna2||DNA helicase|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • dna replication helicase [Schizosaccharomyces pombe]gi|15213981|sp|Q9URU2|DNA2_SCHPO DNA replication helicase dna2gi|7490709|pir||T39568 hypothetical helicase - fission yeast (Schizosaccharomyces pombe)gi|4481950|emb|CAB38508.1| DNA helicase; involved [nrdb_11152004_Chlamydomonas]
  • |dna2||DNA replication helicase Dna2|Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (Q9URU2) DNA replication helicase dna2 [pompep4896_normal_reversed]
  • |dna2||DNA replication endonuclease-helicase Dna2|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC16D10.04c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • DNA replication ATP-dependent helicase dna2 [nr-271106-contam.fasta]
  • hypothetical protein SPBC16D10.04c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
    • Organism: Schizosaccharomyces pombe
    Length: 1398 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article][IDALink to PubMed article]
    nuclear replication fork [ICLink to PubMed article]
    cytosol [IDALink to PubMed article]
    nuclear chromosome, telomeric region [ISSLink to PubMed article]
    Biological Process: DNA repair [ISSLink to PubMed article]
    S phase of mitotic cell cycle [ICLink to PubMed article]
    telomere maintenance [IGILink to PubMed article]
    DNA replication, removal of RNA primer [ISSLink to PubMed article]
    Molecular Function: 5'-flap endonuclease activity [ISSLink to PubMed article]
    ATP binding [ISSLink to PubMed article]
    protein binding [IPILink to PubMed articleLink to PubMed article]
    exonuclease activity [TASLink to PubMed article]
    telomeric DNA binding [IDALink to PubMed article]
    ATP-dependent DNA helicase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFNDQSKTTS SVKGICATTD NNHGNLKKTN STPFRKNYLL NGRTKLKLEN FAYNASTEIS  60
   61 SPKISEKKHS SLPIKRKNTF NESSTSFSPF TKAHKEITDD LKPDKSFTRK SDLNSQDMPE 120
  121 VCFQETSKDL CRSSSTQHLL DHQTTDSTII DMKPVSTNSK SDVFTLYTDE TVLLRRCASD 180
  181 NKPLINNNLS SSNVSENQSR SFGSYDEVKN QGNNLHKVPS LVSIIRNARS SEQSRIAANS 240
  241 SCLLKGSDTE IDEDDFALEA EDLAALDSLE RQYSQLPNST VTASAKDIEK TAKVNHVGGD 300
  301 LQSYCSATKA SDATINEEPV NLALDKACNS LPDINSDFID DWDDSCDGCT PGELCEFSSE 360
  361 YTVLEVHEDF IFHEGNHFRQ LKLILEANDI LHQLFLRGDW TETSIFVGDS IRVEATFDKD 420
  421 NTAIVDNDKG LIIIHPKILM SATAVASSFP CLRKAVISDR VGIYGPPTKA MVTGNILHDF 480
  481 FQHALYRGID ALENVDINLE TSIKTYISDI YFADLSLDEI REELDARLPL LKSIVERYLI 540
  541 SKKNDNNNES IHISRLLDIE ESIWSPRFGL KGNIDATVEV VLTEKPESSS TLTLPLELKT 600
  601 GRYVDNISHF AQSLLYTLLI SDRYGINTNQ ALLCYLENST IKNLVASNSQ LRGLIMTRNS 660
  661 LAQHNFRRSL PEMISNRKIC DHCSLVSECL FFQKMSDKGV ANSNGLTESW NEWMREVKDE 720
  721 DLEFYKKWEK LLNQEERLLL LKRGDVLTFD TEELEAYGKT LYPLYITKED IVCLEIDDRV 780
  781 FHYKFAFLND NGYPRNFLHS GFSVGERVFI SDEHGHWSLA KGHIVHIQDS CIEVRTRHRL 840
  841 HIPWLKMPNF DFKKNQVFFG NYEDSKLSFI GSNHTRYRID KDEFSSGIAS IRGTLMSSVL 900
  901 PDAPLIIRDM IIRLKPPKFC NSALIDPEFL KCLNEDQITA LKKCHAAEHY SLILGMPGTG 960
  961 KTTTISSLIR SLLAKKKKIL LTSFTHLAVD NILIKLKGCD STIVRLGSPH KIHPLVKEFC1020
 1021 LTEGTTFDDL ASLKHFYEDP QIVACSSLGV YHSIFNKRKF DYCIIDEASQ IPLPICLGPL1080
 1081 QLAEKFVLVG DHYQLPPLVK NSRTSKDGLS LSLFKLLSEK HPEAVTTLRL QYRMNEDINS1140
 1141 LSSELIYGGN LVCGSKTISQ KKLILPKAHL SDGLPDSSSS LHWVNKLINP SHSVIFFNTD1200
 1201 DILGVESKTN NILENHTEAF LIEQAVSSFL ERGVKQSSIG IISIYKSQVE LLSKNLKSFT1260
 1261 EIEINTVDRY QGRDKDIILI SFVRSNSKNL VGELLRDWHR LNVALSRAKV KCIMFGSLST1320
 1321 LSSSNIVSHL LKLLEKNKWI FTLNENDIAT KFDENSSPIK DCSQVATTNN AKVIIRKNQR1380
 1381 FFNSDNLCEK AILPQLEF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle