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Protein Overview: alp21

General Information:
Name(s) found: alp21 / SPAC22H10.10 [Sanger Pombe]
Description(s) found:
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  • gi|2851636|sp|Q10303.2|ALP21_SCHPO RecName: Full=Cell polarity protein alp21; AltName: Full=Altered polarity protein 21; AltName: Full=Suppressor of tsm one protein 1 [NCBI NR]
  • gi|2655948|emb|CAA93613.1| tubulin specific chaperone cofactor E [Schizosaccharomyces pombe] [NCBI NR]
  • gi|2618490|dbj|BAA23374.1| Alp21 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19114659|ref|NP_593747.1| tubulin specific chaperone cofactor E [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • pir||T43282 alp21 protein - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • tubulin specific chaperone cofactor E [Sanger Pombe]
  • Cell polarity protein alp21 OS=Schizosaccharomyces pombe GN=alp21 PE=1 SV=2 [Swiss-Prot]
  • (Q10303) Cell polarity protein alp21 (Altered polarity protein 21) (Suppressor of tsm one protein 1) [Swiss-Prot]
  • REQUIRED FOR MICROTUBULAE ASSEMBLY; PUTATIVE TUBULIN-SPECIFIC CHAPERONE; INVOLVED IN FORMATION OF ALPHA- BETA-TUBULIN HETERODIMER; NULL LETHAL; SIMILAR TO S. CEREVISIAE PAC2: Q10303; [pompepVF.fasta]
  • REQUIRED FOR MICROTUBULAE ASSEMBLY; PUTATIVE TUBULIN-SPECIFIC CHAPERONE; INVOLVED IN FORMATION OF ALPHA-BETA-TUBULIN HETERODIMER; NULL LETHAL; SIMIALR TO S. CEREVISIAE PAC2: Q10303; [pompepV13]
  • Cell polarity protein alp21 (Altered polarity protein 21) (Suppressor of tsm one protein 1) [pompep4896]
  • |alp21|sto1|LRR domain [pompepnew.fasta]
  • |alp21|sto1|LRR domain|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • alp21 protein [Schizosaccharomyces pombe]gi|2655948|emb|CAA93613.1| sto1 [Schizosaccharomyces pombe]gi|2851636|sp|Q10303|AL21_SCHPO Cell polarity protein alp21 (Altered polarity protein 21) (Suppressor of tsm one protein 1)gi|11358998|pir||T43282 alp21 [nrdb_11152004_Chlamydomonas]
  • |alp21|sto1|tubulin specific chaperone cofactor E|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • Alp21 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC22H10.10 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPAC22H10.10 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Cell polarity protein alp21 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=alp21 PE=1 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 511 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: post-chaperonin tubulin folding pathway [ISSLink to PubMed article]
    protein folding [TASLink to PubMed article]
    microtubule-based process [RCALink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    alpha-tubulin binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHISTGMVRA SISNTLVTLT IEGNNDRYQV ILDKNVNAKQ FVKTCWRNKK PLIVKEGKIF  60
   61 VDKGFPFDPC RTFLEALYEK YSYSSPLPSS VEFKSGKQVE FCGFEKIQSK QRDLKSLRVI 120
  121 ILDNYRIEDI EIEYEYSKIL PEVIDLDLSR NLFHEFFPIL KLCSQLPSLR NLTLDSNLFS 180
  181 NFISSNTVLL IPHLTQLSVN GCGLNSKDVQ WITETFPSLE VLYLEANEII LSKATSFKNL 240
  241 QFLQTLSLAN NLNLYSADGY AVDVFQGINN LNLSSTSLAD VAELPVHTLH KLTFLDISEN 300
  301 NIRDIRSLDH LRTLENLKHL RITLSYFNKP TDIAKLLVIA RIPSLVKLND VNISPNERLD 360
  361 AELYYTSCIR KLVIDNEIKD VEELTKIEPF WEEIWKSHEL PSIQFHLEAS INDWTSGILK 420
  421 NRITKGIKIS SINSGATMLL KLHYNWKLLD IKALISYHFA IPVHTSTFVF ASSERDVSFS 480
  481 PKTVRDDQKR LFELPFTCTF IDVYAKESGN V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..511] PSI-BLAST 16.221849 The molecular structure of toll-like receptor 3 ligand binding domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle